Association of rhinovirus with exacerbations in young children affected by cystic fibrosis: preliminary data

Sacha Stelzer-Braid; Nancy Liu; Michael Doumit; Russell D'Cunha; Yvonne Belessis; Adam Jaffe; William D. Rawlinson

doi:10.1002/jmv.24794

Association of rhinovirus with exacerbations in young children affected by cystic fibrosis: preliminary data

Sacha Stelzer-Braid^*, Nancy Liu, Michael Doumit, Russell D'Cunha, Yvonne Belessis, Adam Jaffe, William D. Rawlinson

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT-PCR in samples (n = 465) collected from the upper (nasal swab, oropharyngeal suction, and sputum) and lower (bronchoalveolar washings) respiratory tract of 110 children with CF. Air samples (n = 52) collected from the operating theatres and outpatient clinics were tested for RV. RV was found in 43% of children <5 years suffering an exacerbation, and 12% of older children (5-17 years). RV particles were detected in the air of clinic rooms. Detection of RV is important in better understanding viral infections in patients with CF.

Original language	English
Pages (from-to)	1494-1497
Number of pages	4
Journal	Journal of Medical Virology
Volume	89
Issue number	8
DOIs	https://doi.org/10.1002/jmv.24794
Publication status	Published - 1 Aug 2017
Externally published	Yes

Keywords

epidemiology
pathogenesis
respiratory tract
rhinovirus

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10.1002/jmv.24794

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title = "Association of rhinovirus with exacerbations in young children affected by cystic fibrosis: preliminary data",

abstract = "Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT-PCR in samples (n = 465) collected from the upper (nasal swab, oropharyngeal suction, and sputum) and lower (bronchoalveolar washings) respiratory tract of 110 children with CF. Air samples (n = 52) collected from the operating theatres and outpatient clinics were tested for RV. RV was found in 43% of children <5 years suffering an exacerbation, and 12% of older children (5-17 years). RV particles were detected in the air of clinic rooms. Detection of RV is important in better understanding viral infections in patients with CF.",

keywords = "epidemiology, pathogenesis, respiratory tract, rhinovirus",

author = "Sacha Stelzer-Braid and Nancy Liu and Michael Doumit and Russell D'Cunha and Yvonne Belessis and Adam Jaffe and Rawlinson, {William D.}",

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Association of rhinovirus with exacerbations in young children affected by cystic fibrosis : preliminary data. / Stelzer-Braid, Sacha; Liu, Nancy; Doumit, Michael; D'Cunha, Russell; Belessis, Yvonne; Jaffe, Adam; Rawlinson, William D.

In: Journal of Medical Virology, Vol. 89, No. 8, 01.08.2017, p. 1494-1497.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Association of rhinovirus with exacerbations in young children affected by cystic fibrosis

T2 - preliminary data

AU - Stelzer-Braid, Sacha

AU - Liu, Nancy

AU - Doumit, Michael

AU - D'Cunha, Russell

AU - Belessis, Yvonne

AU - Jaffe, Adam

AU - Rawlinson, William D.

PY - 2017/8/1

Y1 - 2017/8/1

N2 - Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT-PCR in samples (n = 465) collected from the upper (nasal swab, oropharyngeal suction, and sputum) and lower (bronchoalveolar washings) respiratory tract of 110 children with CF. Air samples (n = 52) collected from the operating theatres and outpatient clinics were tested for RV. RV was found in 43% of children <5 years suffering an exacerbation, and 12% of older children (5-17 years). RV particles were detected in the air of clinic rooms. Detection of RV is important in better understanding viral infections in patients with CF.

AB - Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT-PCR in samples (n = 465) collected from the upper (nasal swab, oropharyngeal suction, and sputum) and lower (bronchoalveolar washings) respiratory tract of 110 children with CF. Air samples (n = 52) collected from the operating theatres and outpatient clinics were tested for RV. RV was found in 43% of children <5 years suffering an exacerbation, and 12% of older children (5-17 years). RV particles were detected in the air of clinic rooms. Detection of RV is important in better understanding viral infections in patients with CF.

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