Bactericidal and cyclooxygenase inhibitory diterpenes from Eremophila sturtii

Qian Liu, David Harrington, James L. Kohen, Subramanyam Vemulpad, Joanne F. Jamie*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)

Abstract

Two serrulatane diterpenes, 3,8-dihydroxyserrulatic acid (1) and serrulatic acid (2), have been isolated from Eremophila sturtii through bioassay-guided fractionation. These compounds inhibit the inflammation pathway enzymes cyclooxygenase 1 and 2, and exhibit bactericidal activity against Staphylococcus aureus.

Original languageEnglish
Pages (from-to)1256-1261
Number of pages6
JournalPhytochemistry
Volume67
Issue number12
DOIs
Publication statusPublished - Jun 2006

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