Barstar:barnase - a versatile platform for colloidal diamond bioconjugation

Varun K A Sreenivasan, Ekaterina A. Ivukina, Wei Deng, Timothy A. Kelf, Tatyana A. Zdobnova, Sergey V. Lukash, Boris V. Veryugin, Oleg A. Stremovskiy, Andrei V. Zvyagin, Sergey M. Deyev

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

We report on a bioconjugation platform based on a high-affinity protein pair, barstar:barnase (Bs:Bn), that provides a modular design toolkit capable of strong (covalent) and versatile assembly of bio/nanocomplexes. Luminescent nanodiamonds (140 nm) serve as the docking station to synthesize Bs:Bn bioconjugates which are characterized and utilized in several applications, including cell transfection.

Original languageEnglish
Pages (from-to)65-68
Number of pages4
JournalJournal of Materials Chemistry
Volume21
Issue number1
DOIs
Publication statusPublished - 7 Jan 2011

Fingerprint Dive into the research topics of 'Barstar:barnase - a versatile platform for colloidal diamond bioconjugation'. Together they form a unique fingerprint.

Cite this