TY - JOUR
T1 - Behavioral expression of learned fear
T2 - Updating of early memories
AU - Yap, Carol S L
AU - Stapinski, Lexine
AU - Richardson, Rick
PY - 2005/12
Y1 - 2005/12
N2 - The expression of learned fear emerges in a response-specific sequence where freezing occurs before fear potentiated startle (FPS) to an odor conditioned stimulus (CS; Postnatal Day [PN] 16 vs. PN 23; e.g., Hunt, 1997; Richardson, Paxinos, & Lee, 2000). Studies have shown that learned fear is expressed in a manner appropriate to the animal's age at training and not its age at test (Richardson & Fan, 2002; Richardson et al., 2000). Specifically, animals trained with an odor CS at PN 16 exhibit avoidance but not FPS when tested at PN 23. The present study shows that subsequent training with a different CS can "update" an early memory, allowing it to be expressed in a manner appropriate to the animal's age at test. This updating effect appears to be modality specific, whereby the subsequent training must involve a CS of the same sensory modality as the original training.
AB - The expression of learned fear emerges in a response-specific sequence where freezing occurs before fear potentiated startle (FPS) to an odor conditioned stimulus (CS; Postnatal Day [PN] 16 vs. PN 23; e.g., Hunt, 1997; Richardson, Paxinos, & Lee, 2000). Studies have shown that learned fear is expressed in a manner appropriate to the animal's age at training and not its age at test (Richardson & Fan, 2002; Richardson et al., 2000). Specifically, animals trained with an odor CS at PN 16 exhibit avoidance but not FPS when tested at PN 23. The present study shows that subsequent training with a different CS can "update" an early memory, allowing it to be expressed in a manner appropriate to the animal's age at test. This updating effect appears to be modality specific, whereby the subsequent training must involve a CS of the same sensory modality as the original training.
UR - http://www.scopus.com/inward/record.url?scp=31344448467&partnerID=8YFLogxK
U2 - 10.1037/0735-7044.119.6.1467
DO - 10.1037/0735-7044.119.6.1467
M3 - Article
C2 - 16420151
AN - SCOPUS:31344448467
SN - 0735-7044
VL - 119
SP - 1467
EP - 1476
JO - Behavioral Neuroscience
JF - Behavioral Neuroscience
IS - 6
ER -