Biodegradable containers for drug delivery to tumours

I. V. Zelepukin; O. Yu Griaznova; B. V. Parakhonskiy; N. Yu Shilyagina; O. I. Guslyakova; A. B. Volovetskiy; A. V. Zvyagin

doi:10.1109/ICLO54117.2022.9840088

Biodegradable containers for drug delivery to tumours

I. V. Zelepukin, O. Yu Griaznova, B. V. Parakhonskiy, N. Yu Shilyagina, O. I. Guslyakova, A. B. Volovetskiy, A. V. Zvyagin

MQ Photonics Research Centre

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

Abstract

To mitigate the hindered transport of multifunctional diagnostics and therapeutics nanoagents in the tumour tissue, we introduce a new drug delivery concept, which relies on drug container passive accumulation in the tumour vasculature followed by a rapid release of small-molecule payload that penetrates through capillary walls to the tumour interstitium and results in deep penetration in the tumour.

Original language	English
Title of host publication	ICLO 2022
Subtitle of host publication	Proceedings of the 2022 International Conference Laser Optics
Place of Publication	Piscataway, NJ
Publisher	Institute of Electrical and Electronics Engineers (IEEE)
Number of pages	1
ISBN (Electronic)	9781665466646
DOIs	https://doi.org/10.1109/ICLO54117.2022.9840088
Publication status	Published - 2022
Event	2022 International Conference Laser Optics, ICLO 2022 - St. Petersburg, Russian Federation Duration: 20 Jun 2022 → 24 Jun 2022

Publication series

Name	Proceedings of the International Conference Laser Optics
ISSN (Print)	2642-5580

Conference

Conference	2022 International Conference Laser Optics, ICLO 2022
Country/Territory	Russian Federation
City	St. Petersburg
Period	20/06/22 → 24/06/22

Keywords

Drug delivery
Intravital Imaging
Nanomedicine
Theranostics

Access to Document

10.1109/ICLO54117.2022.9840088

Cite this

Zelepukin, I. V., Griaznova, O. Y., Parakhonskiy, B. V., Shilyagina, N. Y., Guslyakova, O. I., Volovetskiy, A. B., & Zvyagin, A. V. (2022). Biodegradable containers for drug delivery to tumours. In ICLO 2022: Proceedings of the 2022 International Conference Laser Optics (Proceedings of the International Conference Laser Optics). Institute of Electrical and Electronics Engineers (IEEE). https://doi.org/10.1109/ICLO54117.2022.9840088

@inproceedings{f6a2f52d8f64411f9e515be5963e8479,

title = "Biodegradable containers for drug delivery to tumours",

abstract = "To mitigate the hindered transport of multifunctional diagnostics and therapeutics nanoagents in the tumour tissue, we introduce a new drug delivery concept, which relies on drug container passive accumulation in the tumour vasculature followed by a rapid release of small-molecule payload that penetrates through capillary walls to the tumour interstitium and results in deep penetration in the tumour. ",

keywords = "Drug delivery, Intravital Imaging, Nanomedicine, Theranostics",

author = "Zelepukin, {I. V.} and Griaznova, {O. Yu} and Parakhonskiy, {B. V.} and Shilyagina, {N. Yu} and Guslyakova, {O. I.} and Volovetskiy, {A. B.} and Zvyagin, {A. V.}",

year = "2022",

doi = "10.1109/ICLO54117.2022.9840088",

language = "English",

series = "Proceedings of the International Conference Laser Optics",

publisher = "Institute of Electrical and Electronics Engineers (IEEE)",

booktitle = "ICLO 2022",

address = "United States",

note = "2022 International Conference Laser Optics, ICLO 2022 ; Conference date: 20-06-2022 Through 24-06-2022",

}

Zelepukin, IV, Griaznova, OY, Parakhonskiy, BV, Shilyagina, NY, Guslyakova, OI, Volovetskiy, AB & Zvyagin, AV 2022, Biodegradable containers for drug delivery to tumours. in ICLO 2022: Proceedings of the 2022 International Conference Laser Optics. Proceedings of the International Conference Laser Optics, Institute of Electrical and Electronics Engineers (IEEE), Piscataway, NJ, 2022 International Conference Laser Optics, ICLO 2022, St. Petersburg, Russian Federation, 20/06/22. https://doi.org/10.1109/ICLO54117.2022.9840088

Biodegradable containers for drug delivery to tumours. / Zelepukin, I. V.; Griaznova, O. Yu; Parakhonskiy, B. V. et al.
ICLO 2022: Proceedings of the 2022 International Conference Laser Optics. Piscataway, NJ: Institute of Electrical and Electronics Engineers (IEEE), 2022. (Proceedings of the International Conference Laser Optics).

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

TY - GEN

T1 - Biodegradable containers for drug delivery to tumours

AU - Zelepukin, I. V.

AU - Griaznova, O. Yu

AU - Parakhonskiy, B. V.

AU - Shilyagina, N. Yu

AU - Guslyakova, O. I.

AU - Volovetskiy, A. B.

AU - Zvyagin, A. V.

PY - 2022

Y1 - 2022

N2 - To mitigate the hindered transport of multifunctional diagnostics and therapeutics nanoagents in the tumour tissue, we introduce a new drug delivery concept, which relies on drug container passive accumulation in the tumour vasculature followed by a rapid release of small-molecule payload that penetrates through capillary walls to the tumour interstitium and results in deep penetration in the tumour.

AB - To mitigate the hindered transport of multifunctional diagnostics and therapeutics nanoagents in the tumour tissue, we introduce a new drug delivery concept, which relies on drug container passive accumulation in the tumour vasculature followed by a rapid release of small-molecule payload that penetrates through capillary walls to the tumour interstitium and results in deep penetration in the tumour.

KW - Drug delivery

KW - Intravital Imaging

KW - Nanomedicine

KW - Theranostics

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U2 - 10.1109/ICLO54117.2022.9840088

DO - 10.1109/ICLO54117.2022.9840088

M3 - Conference proceeding contribution

AN - SCOPUS:85136418825

T3 - Proceedings of the International Conference Laser Optics

BT - ICLO 2022

PB - Institute of Electrical and Electronics Engineers (IEEE)

CY - Piscataway, NJ

T2 - 2022 International Conference Laser Optics, ICLO 2022

Y2 - 20 June 2022 through 24 June 2022

ER -

Zelepukin IV, Griaznova OY, Parakhonskiy BV, Shilyagina NY, Guslyakova OI, Volovetskiy AB et al. Biodegradable containers for drug delivery to tumours. In ICLO 2022: Proceedings of the 2022 International Conference Laser Optics. Piscataway, NJ: Institute of Electrical and Electronics Engineers (IEEE). 2022. (Proceedings of the International Conference Laser Optics). doi: 10.1109/ICLO54117.2022.9840088

Biodegradable containers for drug delivery to tumours

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