Bioproducts From Euglena gracilis: synthesis and applications

Alexander Gissibl, Angela Sun, Andrew Care, Helena Nevalainen, Anwar Sunna

Research output: Contribution to journalReview articlepeer-review

14 Citations (Scopus)
48 Downloads (Pure)


In recent years, the versatile phototrophic protist Euglena gracilis has emerged as an interesting candidate for application-driven research and commercialisation, as it is an excellent source of dietary protein, pro(vitamins), lipids, and the β-1,3-glucan paramylon only found in euglenoids. From these, paramylon is already marketed as an immunostimulatory agent in nutraceuticals. Bioproducts from E. gracilis can be produced under various cultivation conditions discussed in this review, and their yields are relatively high when compared with those achieved in microalgal systems. Future challenges include achieving the economy of large-scale cultivation. Recent insights into the complex metabolism of E. gracilis have highlighted unique metabolic pathways, which could provide new leads for product enhancement by genetic modification of the organism. Also, development of molecular tools for strain improvement are emerging rapidly, making E. gracilis a noteworthy challenger for microalgae such as Chlorella spp. and their products currently on the market.
Original languageEnglish
Article number108
Pages (from-to)1-16
Number of pages16
JournalFrontiers in Bioengineering and Biotechnology
Publication statusPublished - 15 May 2019

Bibliographical note

Copyright the Author(s) 2019. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.


  • Euglena gracilis
  • biosynthesis
  • dietary protein
  • vitamins
  • polyunsaturated fatty acids
  • wax esters
  • paramylon
  • large-scale cultivation

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