Bioprospecting and testing of new fly species for maggot therapy

Patricia J. Thyssen, Franciéle S. Masiero, Frank Stadler

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

5 Citations (Scopus)
82 Downloads (Pure)

Abstract

Lucilia sericata, the green bottle blowfly, has a long history of clinical use and an excellent safety record which makes it safe for therapeutic clinical use. In regions where it is naturally absent, maggot therapy cannot be offered to patients with chronic wounds unless an alternative local species is found. This chapter explains how new species are identified and tested for their therapeutic efficacy and clinical safety. The process involves the bioprospecting for candidate fly species, pre-clinical in vitro and animal studies to make sure they are therapeutically active and safe, and clinical trials of maggot therapy with human patients.
Original languageEnglish
Title of host publicationA Complete Guide to Maggot Therapy
Subtitle of host publicationClinical Practice, Therapeutic Principles, Production, Distribution, and Ethics
EditorsFrank Stadler
Place of PublicationCambridge
PublisherOpen Book Publishers
Chapter11
Pages195-234
Number of pages40
ISBN (Electronic)9781800647305, 9781800647312, 9781800647329
ISBN (Print)9781800647282, 9781800647299
DOIs
Publication statusPublished - 2022

Bibliographical note

Copyright the Author(s) 2022. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

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