Bioresorbable composite polymeric materials for tissue engineering applications

Sakineh Hajebi, SAeed Mohammadi Nasr, Navid Rabiee, Mojtaba Bagherzadeh, Sepideh Ahmadi, Mohammad Rabiee, Mohammadreza Tahriri*, Lobat Tayebi, Michael R. Hamblin*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

This review covers the development of bioresorbable polymeric composites for applications in tissue engineering. Various commercially available bioresobable polymers are described, with emphasis on recent bioresorbable composites based on natural and synthetic polymers. Bioresorbable polymers contain hydrolyzable bonds, which are subjected to chemical degradation via either reactive hydrolysis or enzyme-catalyzed active hydrolysis. For synthetic polymers, chemical hydrolysis is the most important mode of degradation. The degradation rate can be controlled by varying the molecular weight and crystallinity. Examples of bioresorbable polymers are: polyurethane, poly(D,L)lactide, poly(lactic-co-glycolic) acid, poly(α-hydroxy acids), cross-linked polyester hydrogels, poly(orthoesters), polyanhydrides and polyethylene glycol.

Original languageEnglish
Pages (from-to)926-940
Number of pages15
JournalInternational Journal of Polymeric Materials and Polymeric Biomaterials
Volume70
Issue number13
DOIs
Publication statusPublished - 2021
Externally publishedYes

Keywords

  • Biodegradable polymer
  • bioresorbable
  • tissue engineering
  • composite

Fingerprint

Dive into the research topics of 'Bioresorbable composite polymeric materials for tissue engineering applications'. Together they form a unique fingerprint.

Cite this