@inproceedings{2850e600f14b48c2b9e01ebe0ac55303,
title = "Blood culture ordering after sepsis alerts and subsequent patient outcomes: an electronic health record-based study",
abstract = "Sepsis is a global health priority associated with high mortality. Clinical decision support systems have been developed to support clinicians with sepsis management. Ordering blood cultures (BCs) for suspected sepsis patients are strongly recommended by clinical guidelines. However, limited evidence exists investigating BC ordering following sepsis alerts and subsequent patient outcomes. This study aimed to investigate this issue using electronic health record data from an acute care hospital in Australia. Of 4,092 patients, only 16.6% had a BC ordered following a sepsis alert. The median time from the first sepsis alert to a BC order was 15.3 hours. Patients had 5.89 times higher odds of being diagnosed with sepsis if a BC was ordered following a sepsis alert than those without BC ordered (p<0.0001). Further investigation is needed to understand reasons behind the delay or failure to order a BC despite receiving electronic sepsis alerts and how decision support can be optimized to improve patient outcomes.",
keywords = "Sepsis, computerized clinical decision support, blood culture, antibiotics appropriateness",
author = "Ling Li and Kasun Rathnayake and Scott Walter and Mary Fullick and Amith Shetty and Paul Hudson and Harvey Lander and Westbrook, {Johanna I.}",
note = "Copyright the International Medical Informatics Association (IMIA) and IOS Press 2024. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.; MEDINFO 2023 ; Conference date: 08-07-2023 Through 12-07-2023",
year = "2024",
month = jan,
day = "25",
doi = "10.3233/SHTI230978",
language = "English",
isbn = "9781643684567",
series = "Studies in Health Technology and Informatics",
publisher = "IOS Press",
pages = "314--318",
editor = "Jen Bichel-Findlay and Paula Otero and Philip Scott and Elaine Huesing",
booktitle = "MEDINFO 2023 - The future is accessible",
address = "United States",
}