Botulinum toxin A in functional popliteal entrapment syndrome: a new approach to a difficult diagnosis

Florin Gandor; Stephen Tisch; Anthony J. Grabs; Anthony J. Delaney; Lourens Bester; Paul Darveniza

doi:10.1007/s00702-014-1197-z

Botulinum toxin A in functional popliteal entrapment syndrome: a new approach to a difficult diagnosis

Florin Gandor, Stephen Tisch, Anthony J. Grabs, Anthony J. Delaney, Lourens Bester, Paul Darveniza

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Functional Popliteal Entrapment Syndrome (FPES) is caused by compression of neurovascular structures in the popliteal fossa by hypertrophic muscles, provoking severe leg pain with exercise. Treatment is limited to myotomy of hypertrophic musculature. 8 FPES patients underwent imaging and exercise studies, before receiving botulinum toxin A injections (BTX-A) into the gastrocnemius and plantaris muscles. 81.3 % of patients reported clinical improvement on follow-up, and pathological ankle–brachial indices were normalized. BTX-A injection may present a new, safe, effective and non-invasive approach to FPES.

Original language	English
Pages (from-to)	1297-1301
Number of pages	5
Journal	Journal of Neural Transmission
Volume	121
DOIs	https://doi.org/10.1007/s00702-014-1197-z
Publication status	Published - Mar 2014
Externally published	Yes

Keywords

Functional Popliteal Entrapment Syndrome
Botulinum toxin A
Ankle–brachial index
Claudication
Treatment

Access to Document

10.1007/s00702-014-1197-z

Cite this

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title = "Botulinum toxin A in functional popliteal entrapment syndrome: a new approach to a difficult diagnosis",

abstract = "Functional Popliteal Entrapment Syndrome (FPES) is caused by compression of neurovascular structures in the popliteal fossa by hypertrophic muscles, provoking severe leg pain with exercise. Treatment is limited to myotomy of hypertrophic musculature. 8 FPES patients underwent imaging and exercise studies, before receiving botulinum toxin A injections (BTX-A) into the gastrocnemius and plantaris muscles. 81.3 % of patients reported clinical improvement on follow-up, and pathological ankle–brachial indices were normalized. BTX-A injection may present a new, safe, effective and non-invasive approach to FPES.",

keywords = "Functional Popliteal Entrapment Syndrome, Botulinum toxin A, Ankle–brachial index, Claudication, Treatment",

author = "Florin Gandor and Stephen Tisch and Grabs, {Anthony J.} and Delaney, {Anthony J.} and Lourens Bester and Paul Darveniza",

year = "2014",

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language = "English",

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journal = "Journal of Neural Transmission",

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T1 - Botulinum toxin A in functional popliteal entrapment syndrome

T2 - a new approach to a difficult diagnosis

AU - Gandor, Florin

AU - Tisch, Stephen

AU - Grabs, Anthony J.

AU - Delaney, Anthony J.

AU - Bester, Lourens

AU - Darveniza, Paul

PY - 2014/3

Y1 - 2014/3

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AB - Functional Popliteal Entrapment Syndrome (FPES) is caused by compression of neurovascular structures in the popliteal fossa by hypertrophic muscles, provoking severe leg pain with exercise. Treatment is limited to myotomy of hypertrophic musculature. 8 FPES patients underwent imaging and exercise studies, before receiving botulinum toxin A injections (BTX-A) into the gastrocnemius and plantaris muscles. 81.3 % of patients reported clinical improvement on follow-up, and pathological ankle–brachial indices were normalized. BTX-A injection may present a new, safe, effective and non-invasive approach to FPES.

KW - Functional Popliteal Entrapment Syndrome

KW - Botulinum toxin A

KW - Ankle–brachial index

KW - Claudication

KW - Treatment

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DO - 10.1007/s00702-014-1197-z

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SN - 0300-9564

VL - 121

SP - 1297

EP - 1301

JO - Journal of Neural Transmission

JF - Journal of Neural Transmission

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