Brain mechanisms underlying phonological treatment effects in aphasia

David Copland, Katie McMahon, Greig de Zubicaray, Lyndsey Nickels, Erin Smith

    Research output: Contribution to journalMeeting abstract


    A functional MRI-naming paradigm was employed to investigate the neural correlates of successful phonological treatment in an individual with impaired word-retrieval poststroke. Items to be treated were selected in a pretest. A subsequent pretreatment fMRI scan measured brain activity during unsuccessful naming of objects to be treated and during successful naming of a comparison set of items. A phonological naming treatment was delivered 2 to 3 times weekly over 3 weeks with posttreatment behavioural testing indicating 100% accuracy on treated items. A posttreatment fMRI scan indicated that compared to the pretreatment scan, successful naming of treated items was associated with significantly increased brain activity in a number of left and right hemisphere regions including the left inferior parietal cortex which has been associated with phonological processing in healthy individuals, suggesting a candidate neural mechanism for sound-based treatments of naming.
    Original languageEnglish
    Pages (from-to)263
    Number of pages1
    JournalBrain impairment : abstracts from Aphasiology Symposium of Australia
    Issue number3
    Publication statusPublished - 2006
    EventAphasiology Symposium of Australia - Sydney
    Duration: 30 Nov 20061 Dec 2006


    • neurogenic communication disorders
    • communicative disorders
    • language disorders
    • speech therapy


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