Brain mechanisms underlying phonological treatment effects in aphasia

David Copland; Katie McMahon; Greig de Zubicaray; Lyndsey Nickels; Erin Smith

Abstract

A functional MRI-naming paradigm was employed to investigate the neural correlates of successful phonological treatment in an individual with impaired word-retrieval poststroke. Items to be treated were selected in a pretest. A subsequent pretreatment fMRI scan measured brain activity during unsuccessful naming of objects to be treated and during successful naming of a comparison set of items. A phonological naming treatment was delivered 2 to 3 times weekly over 3 weeks with posttreatment behavioural testing indicating 100% accuracy on treated items. A posttreatment fMRI scan indicated that compared to the pretreatment scan, successful naming of treated items was associated with significantly increased brain activity in a number of left and right hemisphere regions including the left inferior parietal cortex which has been associated with phonological processing in healthy individuals, suggesting a candidate neural mechanism for sound-based treatments of naming.

Original language	English
Pages (from-to)	263
Number of pages	1
Journal	Brain impairment : abstracts from Aphasiology Symposium of Australia
Volume	7
Issue number	3
Publication status	Published - 2006
Event	Aphasiology Symposium of Australia - Sydney Duration: 30 Nov 2006 → 1 Dec 2006

Keywords

neurogenic communication disorders
communicative disorders
language disorders
speech therapy

Cite this

@article{1148363cee3242959f8f29e5cc2f2077,

title = "Brain mechanisms underlying phonological treatment effects in aphasia",

abstract = "A functional MRI-naming paradigm was employed to investigate the neural correlates of successful phonological treatment in an individual with impaired word-retrieval poststroke. Items to be treated were selected in a pretest. A subsequent pretreatment fMRI scan measured brain activity during unsuccessful naming of objects to be treated and during successful naming of a comparison set of items. A phonological naming treatment was delivered 2 to 3 times weekly over 3 weeks with posttreatment behavioural testing indicating 100\% accuracy on treated items. A posttreatment fMRI scan indicated that compared to the pretreatment scan, successful naming of treated items was associated with significantly increased brain activity in a number of left and right hemisphere regions including the left inferior parietal cortex which has been associated with phonological processing in healthy individuals, suggesting a candidate neural mechanism for sound-based treatments of naming.",

keywords = "neurogenic communication disorders, communicative disorders, language disorders, speech therapy",

author = "David Copland and Katie McMahon and \{de Zubicaray\}, Greig and Lyndsey Nickels and Erin Smith",

year = "2006",

language = "English",

volume = "7",

pages = "263",

journal = "Brain impairment : abstracts from Aphasiology Symposium of Australia",

issn = "1443-9646",

publisher = "Australian Society for the Study of Brain Impairment",

number = "3",

note = "Aphasiology Symposium of Australia ; Conference date: 30-11-2006 Through 01-12-2006",

}

TY - JOUR

T1 - Brain mechanisms underlying phonological treatment effects in aphasia

AU - Copland, David

AU - McMahon, Katie

AU - de Zubicaray, Greig

AU - Nickels, Lyndsey

AU - Smith, Erin

PY - 2006

Y1 - 2006

N2 - A functional MRI-naming paradigm was employed to investigate the neural correlates of successful phonological treatment in an individual with impaired word-retrieval poststroke. Items to be treated were selected in a pretest. A subsequent pretreatment fMRI scan measured brain activity during unsuccessful naming of objects to be treated and during successful naming of a comparison set of items. A phonological naming treatment was delivered 2 to 3 times weekly over 3 weeks with posttreatment behavioural testing indicating 100% accuracy on treated items. A posttreatment fMRI scan indicated that compared to the pretreatment scan, successful naming of treated items was associated with significantly increased brain activity in a number of left and right hemisphere regions including the left inferior parietal cortex which has been associated with phonological processing in healthy individuals, suggesting a candidate neural mechanism for sound-based treatments of naming.

AB - A functional MRI-naming paradigm was employed to investigate the neural correlates of successful phonological treatment in an individual with impaired word-retrieval poststroke. Items to be treated were selected in a pretest. A subsequent pretreatment fMRI scan measured brain activity during unsuccessful naming of objects to be treated and during successful naming of a comparison set of items. A phonological naming treatment was delivered 2 to 3 times weekly over 3 weeks with posttreatment behavioural testing indicating 100% accuracy on treated items. A posttreatment fMRI scan indicated that compared to the pretreatment scan, successful naming of treated items was associated with significantly increased brain activity in a number of left and right hemisphere regions including the left inferior parietal cortex which has been associated with phonological processing in healthy individuals, suggesting a candidate neural mechanism for sound-based treatments of naming.

KW - neurogenic communication disorders

KW - communicative disorders

KW - language disorders

KW - speech therapy

UR - https://doi.org/10.1375/brim.7.3.259

M3 - Meeting abstract

SN - 1443-9646

VL - 7

SP - 263

JO - Brain impairment : abstracts from Aphasiology Symposium of Australia

JF - Brain impairment : abstracts from Aphasiology Symposium of Australia

IS - 3

T2 - Aphasiology Symposium of Australia

Y2 - 30 November 2006 through 1 December 2006

ER -

Brain mechanisms underlying phonological treatment effects in aphasia

Abstract

Keywords

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