Abstract
Lanthanide-doped upconversion nanoparticles (UCNPs) are capable of converting near-infrared (NIR) excitation to visible and ultraviolet emission via stepwise multiphoton processes. They offer unique advantages (e.g. sharp emission bands, superb photostability and long lifetimes1) compared to conventional dyes and quantum dots, enabling advanced detection and imaging for biologically important molecules. However, their application to live cells and small animals has been practically limited due to the potential damage under high-power laser illumination, as well as concerns for life scientists who do not necessary possess sufficient knowledge and experience in laser safety. Therefore, we have been exploring new strategies to develop UCNPs that are capable of excitation by incoherent sources such as light-emitting diodes (LEDs), in particular via increased number of sensitizer ions and coating of inert shells.
Original language | English |
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Title of host publication | Biophotonics Australasia 2019 |
Editors | Ewa M. Goldys, Brant C. Gibson |
Place of Publication | Bellingham : WA |
Publisher | SPIE |
Number of pages | 2 |
Volume | 11202 |
ISBN (Electronic) | 9781510631458 |
ISBN (Print) | 9781510631441 |
DOIs | |
Publication status | Published - 2019 |
Event | Biophotonics Australasia 2019 - Melbourne, Australia Duration: 9 Dec 2019 → 12 Dec 2019 |
Conference
Conference | Biophotonics Australasia 2019 |
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Country/Territory | Australia |
City | Melbourne |
Period | 9/12/19 → 12/12/19 |