Bright upconversion nanoparticles under light-emitting diode excitation

Yueying Cao, Xianlin Zheng, James A. Piper, Nicolle H. Packer, Yiqing Lu*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference abstract

Abstract

Lanthanide-doped upconversion nanoparticles (UCNPs) are capable of converting near-infrared (NIR) excitation to visible and ultraviolet emission via stepwise multiphoton processes. They offer unique advantages (e.g. sharp emission bands, superb photostability and long lifetimes1) compared to conventional dyes and quantum dots, enabling advanced detection and imaging for biologically important molecules. However, their application to live cells and small animals has been practically limited due to the potential damage under high-power laser illumination, as well as concerns for life scientists who do not necessary possess sufficient knowledge and experience in laser safety. Therefore, we have been exploring new strategies to develop UCNPs that are capable of excitation by incoherent sources such as light-emitting diodes (LEDs), in particular via increased number of sensitizer ions and coating of inert shells.

Original languageEnglish
Title of host publicationBiophotonics Australasia 2019
EditorsEwa M. Goldys, Brant C. Gibson
Place of PublicationBellingham : WA
PublisherSPIE
Number of pages2
Volume11202
ISBN (Electronic)9781510631458
ISBN (Print)9781510631441
DOIs
Publication statusPublished - 2019
EventBiophotonics Australasia 2019 - Melbourne, Australia
Duration: 9 Dec 201912 Dec 2019

Conference

ConferenceBiophotonics Australasia 2019
CountryAustralia
CityMelbourne
Period9/12/1912/12/19

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