It is presently unknown whether inspiration extends across different domains: can a salesperson, for example, be inspired by a successful athlete? The present study investigated whether inspirational content must be relevant to a subsequent task to improve performance. Participants (N = 70) wrote about a time they felt inspired in a sporting context (domain-relevant), creative context (domain-irrelevant); or amused (positive control). Participants then held a handgrip, with the option of giving up or continuing to exhaustion. Regardless of the relevance of the inspirational content to the performance task, inspired participants were less likely to give up than controls. This is the first research to show that the benefits of inspiration reach beyond the domain defined by the inspiring event.