Care after premenopausal risk‐reducing salpingo‐oophorectomy in high‐risk women: scoping review and international consensus recommendations

Denise R. Nebgen; Susan M. Domchek; Joanne Kotsopoulos; Joanne A. de Hullu; Emma J. Crosbie; Vincent Singh Paramanandam; Monique M. A. Brood ‐ van Zanten; Barbara M. Norquist; Theresa Guise; Serge Rozenberg; Allison W. Kurian; Holly J. Pederson; Nese Yuksel; Rachel Michaelson‐Cohen; Sharon L. Bober; Agnaldo Lopes da Silva Filho; Nora Johansen; F. Guidozzi; D. Gareth Evans; Usha Menon; Sheryl A. Kingsberg; C. Bethan Powell; Giovanni Grandi; Claudia Marchetti; Michelle Jacobson; Donal J. Brennan; Martha Hickey

doi:10.1111/1471-0528.17511

Care after premenopausal risk‐reducing salpingo‐oophorectomy in high‐risk women: scoping review and international consensus recommendations

Denise R. Nebgen, Susan M. Domchek, Joanne Kotsopoulos, Joanne A. de Hullu, Emma J. Crosbie, Vincent Singh Paramanandam, Monique M. A. Brood ‐ van Zanten, Barbara M. Norquist, Theresa Guise, Serge Rozenberg, Allison W. Kurian, Holly J. Pederson, Nese Yuksel, Rachel Michaelson‐Cohen, Sharon L. Bober, Agnaldo Lopes da Silva Filho, Nora Johansen, F. Guidozzi, D. Gareth Evans, Usha MenonSheryl A. Kingsberg, C. Bethan Powell, Giovanni Grandi, Claudia Marchetti, Michelle Jacobson, Donal J. Brennan, Martha Hickey

Research output: Contribution to journal › Review article › peer-review

17 Citations (Scopus)

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Abstract

Women at high inherited risk of ovarian cancer are offered risk-reducing salpingo-oophorectomy (RRSO) from age 35 to 45 years. Although potentially life-saving, RRSO may induce symptoms that negatively affect quality of life and impair long-term health. Clinical care following RRSO is often suboptimal. This scoping review describes how RRSO affects short- and long-term health and provides evidence-based international consensus recommendations for care from preoperative counselling to long-term disease prevention. This includes the efficacy and safety of hormonal and non-hormonal treatments for vasomotor symptoms, sleep disturbance and sexual dysfunction and effective approaches to prevent bone and cardiovascular disease.

Original language	English
Pages (from-to)	1437-1450
Number of pages	14
Journal	BJOG: An International Journal of Obstetrics & Gynaecology
Volume	130
Issue number	12
DOIs	https://doi.org/10.1111/1471-0528.17511
Publication status	Published - Nov 2023
Externally published	Yes

Bibliographical note

Copyright the Author(s) 2023. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

BRCA1
BRCA2
early menopause
hormone replacement therapy
hot flushes
ovarian cancer
risk-reducing salpingo-oophorectomy
sexual function
surgical menopause

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10.1111/1471-0528.17511Licence: CC BY

Publisher version (open access)Final published version, 994 KBLicence: CC BY

Cite this

Nebgen, D. R., Domchek, S. M., Kotsopoulos, J., Hullu, J. A. D., Crosbie, E. J., Paramanandam, V. S., Brood ‐ van Zanten, M. M. A., Norquist, B. M., Guise, T., Rozenberg, S., Kurian, A. W., Pederson, H. J., Yuksel, N., Michaelson‐Cohen, R., Bober, S. L., Silva Filho, A. L. D., Johansen, N., Guidozzi, F., Evans, D. G., ... Hickey, M. (2023). Care after premenopausal risk‐reducing salpingo‐oophorectomy in high‐risk women: scoping review and international consensus recommendations. BJOG: An International Journal of Obstetrics & Gynaecology, 130(12), 1437-1450. https://doi.org/10.1111/1471-0528.17511

@article{e30687e0fe0a4e9fab8568d8f7440d24,

title = "Care after premenopausal risk‐reducing salpingo‐oophorectomy in high‐risk women: scoping review and international consensus recommendations",

abstract = "Women at high inherited risk of ovarian cancer are offered risk-reducing salpingo-oophorectomy (RRSO) from age 35 to 45 years. Although potentially life-saving, RRSO may induce symptoms that negatively affect quality of life and impair long-term health. Clinical care following RRSO is often suboptimal. This scoping review describes how RRSO affects short- and long-term health and provides evidence-based international consensus recommendations for care from preoperative counselling to long-term disease prevention. This includes the efficacy and safety of hormonal and non-hormonal treatments for vasomotor symptoms, sleep disturbance and sexual dysfunction and effective approaches to prevent bone and cardiovascular disease.",

keywords = "BRCA1, BRCA2, early menopause, hormone replacement therapy, hot flushes, ovarian cancer, risk-reducing salpingo-oophorectomy, sexual function, surgical menopause",

author = "Nebgen, {Denise R.} and Domchek, {Susan M.} and Joanne Kotsopoulos and Hullu, {Joanne A. de} and Crosbie, {Emma J.} and Paramanandam, {Vincent Singh} and {Brood ‐ van Zanten}, {Monique M. A.} and Norquist, {Barbara M.} and Theresa Guise and Serge Rozenberg and Kurian, {Allison W.} and Pederson, {Holly J.} and Nese Yuksel and Rachel Michaelson‐Cohen and Bober, {Sharon L.} and Silva Filho, {Agnaldo Lopes da} and Nora Johansen and F. Guidozzi and Evans, {D. Gareth} and Usha Menon and Kingsberg, {Sheryl A.} and Powell, {C. Bethan} and Giovanni Grandi and Claudia Marchetti and Michelle Jacobson and Brennan, {Donal J.} and Martha Hickey",

note = "Copyright the Author(s) 2023. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.",

year = "2023",

month = nov,

doi = "10.1111/1471-0528.17511",

language = "English",

volume = "130",

pages = "1437--1450",

journal = "BJOG: An International Journal of Obstetrics & Gynaecology",

issn = "1470-0328",

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}

Nebgen, DR, Domchek, SM, Kotsopoulos, J, Hullu, JAD, Crosbie, EJ, Paramanandam, VS, Brood ‐ van Zanten, MMA, Norquist, BM, Guise, T, Rozenberg, S, Kurian, AW, Pederson, HJ, Yuksel, N, Michaelson‐Cohen, R, Bober, SL, Silva Filho, ALD, Johansen, N, Guidozzi, F, Evans, DG, Menon, U, Kingsberg, SA, Powell, CB, Grandi, G, Marchetti, C, Jacobson, M, Brennan, DJ & Hickey, M 2023, 'Care after premenopausal risk‐reducing salpingo‐oophorectomy in high‐risk women: scoping review and international consensus recommendations', BJOG: An International Journal of Obstetrics & Gynaecology, vol. 130, no. 12, pp. 1437-1450. https://doi.org/10.1111/1471-0528.17511

Care after premenopausal risk‐reducing salpingo‐oophorectomy in high‐risk women: scoping review and international consensus recommendations. / Nebgen, Denise R.; Domchek, Susan M.; Kotsopoulos, Joanne et al.
In: BJOG: An International Journal of Obstetrics & Gynaecology, Vol. 130, No. 12, 11.2023, p. 1437-1450.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Care after premenopausal risk‐reducing salpingo‐oophorectomy in high‐risk women

T2 - scoping review and international consensus recommendations

AU - Nebgen, Denise R.

AU - Domchek, Susan M.

AU - Kotsopoulos, Joanne

AU - Hullu, Joanne A. de

AU - Crosbie, Emma J.

AU - Paramanandam, Vincent Singh

AU - Brood ‐ van Zanten, Monique M. A.

AU - Norquist, Barbara M.

AU - Guise, Theresa

AU - Rozenberg, Serge

AU - Kurian, Allison W.

AU - Pederson, Holly J.

AU - Yuksel, Nese

AU - Michaelson‐Cohen, Rachel

AU - Bober, Sharon L.

AU - Silva Filho, Agnaldo Lopes da

AU - Johansen, Nora

AU - Guidozzi, F.

AU - Evans, D. Gareth

AU - Menon, Usha

AU - Kingsberg, Sheryl A.

AU - Powell, C. Bethan

AU - Grandi, Giovanni

AU - Marchetti, Claudia

AU - Jacobson, Michelle

AU - Brennan, Donal J.

AU - Hickey, Martha

N1 - Copyright the Author(s) 2023. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

PY - 2023/11

Y1 - 2023/11

N2 - Women at high inherited risk of ovarian cancer are offered risk-reducing salpingo-oophorectomy (RRSO) from age 35 to 45 years. Although potentially life-saving, RRSO may induce symptoms that negatively affect quality of life and impair long-term health. Clinical care following RRSO is often suboptimal. This scoping review describes how RRSO affects short- and long-term health and provides evidence-based international consensus recommendations for care from preoperative counselling to long-term disease prevention. This includes the efficacy and safety of hormonal and non-hormonal treatments for vasomotor symptoms, sleep disturbance and sexual dysfunction and effective approaches to prevent bone and cardiovascular disease.

AB - Women at high inherited risk of ovarian cancer are offered risk-reducing salpingo-oophorectomy (RRSO) from age 35 to 45 years. Although potentially life-saving, RRSO may induce symptoms that negatively affect quality of life and impair long-term health. Clinical care following RRSO is often suboptimal. This scoping review describes how RRSO affects short- and long-term health and provides evidence-based international consensus recommendations for care from preoperative counselling to long-term disease prevention. This includes the efficacy and safety of hormonal and non-hormonal treatments for vasomotor symptoms, sleep disturbance and sexual dysfunction and effective approaches to prevent bone and cardiovascular disease.

KW - BRCA1

KW - BRCA2

KW - early menopause

KW - hormone replacement therapy

KW - hot flushes

KW - ovarian cancer

KW - risk-reducing salpingo-oophorectomy

KW - sexual function

KW - surgical menopause

UR - http://www.scopus.com/inward/record.url?scp=85158081710&partnerID=8YFLogxK

U2 - 10.1111/1471-0528.17511

DO - 10.1111/1471-0528.17511

M3 - Review article

C2 - 37132126

SN - 1470-0328

VL - 130

SP - 1437

EP - 1450

JO - BJOG: An International Journal of Obstetrics & Gynaecology

JF - BJOG: An International Journal of Obstetrics & Gynaecology

IS - 12

ER -

Care after premenopausal risk‐reducing salpingo‐oophorectomy in high‐risk women: scoping review and international consensus recommendations

Abstract

Bibliographical note

Keywords

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