Carotid artery applanation tonometry does not cause significant baroreceptor activation

Bart Spronck*, Tammo Delhaas, Jos Op't Roodt, Koen D. Reesink

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

BACKGROUND Carotid artery applanation tonometry is widely used in estimating local carotid artery pressure waveforms and carotid-femoral pulse wave velocity. However, the substantial pressure applied locally to the carotid artery with applanation tonometry might well evoke a baroreceptor response, resulting in bradycardia and hypotension. Therefore, when carotid and femoral tonometry are performed sequentially, baroreceptor activation could lead to different hemodynamic conditions between carotid and femoral acquisitions. Combining those acquisitions into one pulse wave velocity measure would be erroneous. In this study, we assessed whether carotid applanation tonometry has an influence on heart rate and blood pressure.

METHODS In 26 hypertensive subjects, heart rate and blood pressure were assessed by continuous finger pulse waveform recording during carotid as well as femoral applanation tonometry. Both carotid and femoral acquisitions were measured in alternation and in triplicate. Median averaging over the 3 carotid and femoral measurements, respectively, was used to obtain a subject's median heart rate and blood pressure during carotid as well as femoral tonometry.

RESULTS Difference in heart rate during carotid and femoral tonometry was -0.7 +/- 2.2 bpm. Differences in systolic, pulse, and diastolic blood pressure were -0.7 +/- 6.8, -0.1 +/- 3.8, and -0.3 +/- 3.5mm Hg, respectively. All differences were statistically nonsignificant. Confidence intervals were used to calculate the maximum absolute difference at 95% certainty, which was 1.6 bpm for heart rate and

CONCLUSIONS We conclude that in our study, carotid artery applanation tonometry as performed by an experienced researcher did not cause clinically significant baroreceptor activation.

Original languageEnglish
Pages (from-to)299-302
Number of pages4
JournalAmerican Journal of Hypertension
Volume29
Issue number3
DOIs
Publication statusPublished - Mar 2016
Externally publishedYes

Keywords

  • applanation tonometry
  • baroreceptor activation
  • baroreflex
  • blood pressure
  • carotid artery
  • hypertension
  • pulse wave velocity
  • PULSE-WAVE VELOCITY
  • HEART-RATE
  • STIFFNESS
  • SINUS

Cite this