Carriers for DPIs: formulation and regulatory challenges

J. S. Kaerger; R. Price; P. M. Young; S. Edge; M. J. Tobyn

Carriers for DPIs: formulation and regulatory challenges

J. S. Kaerger, R. Price, P. M. Young, S. Edge, M. J. Tobyn

Research output: Contribution to journal › Article › peer-review

Abstract

Lactose, in particular alpha-lactose monohydrate, is typically used as 'the' carrier in dry powder inhalers. Even though these often tailored materials allow the delivery of medicines to the body in doses that are much lower than by 'conventional' solid dosage forms, the use of this excipient in this application is posing characterization and regulatory challenges to both suppliers and users.

Original language	English
Pages (from-to)	25-30
Number of pages	6
Journal	Pharmaceutical Technology Europe
Volume	18
Issue number	10
Publication status	Published - 1 Oct 2006
Externally published	Yes

Keywords

Dry Powder Inhalers
Spray Drying
Inhalation

Cite this

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title = "Carriers for DPIs: formulation and regulatory challenges",

abstract = "Lactose, in particular alpha-lactose monohydrate, is typically used as 'the' carrier in dry powder inhalers. Even though these often tailored materials allow the delivery of medicines to the body in doses that are much lower than by 'conventional' solid dosage forms, the use of this excipient in this application is posing characterization and regulatory challenges to both suppliers and users.",

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AU - Price, R.

AU - Young, P. M.

AU - Edge, S.

AU - Tobyn, M. J.

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AB - Lactose, in particular alpha-lactose monohydrate, is typically used as 'the' carrier in dry powder inhalers. Even though these often tailored materials allow the delivery of medicines to the body in doses that are much lower than by 'conventional' solid dosage forms, the use of this excipient in this application is posing characterization and regulatory challenges to both suppliers and users.

KW - Dry Powder Inhalers

KW - Spray Drying

KW - Inhalation

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Carriers for DPIs: formulation and regulatory challenges

Abstract

Keywords

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