Catheter ablation for atrial fibrillation

Stuart P. Thomas, Prashanthan Sanders

    Research output: Contribution to journalArticlepeer-review

    10 Citations (Scopus)


    Atrial fibrillation (AF) is the most common clinically important cardiac arrhythmia. It is an important cause of stroke, contributes to the burden of heart failure and is a major contributor to health expenditure. Percutaneous catheter ablation is superior to medical therapy in reducing AF recurrences. It has an important role in treatment of patients with failed drug therapy. Successful catheter ablation improves left ventricular function in patients with heart failure. In addition, it may be appropriate for selected highly symptomatic patients as first line therapy. Catheter ablation for AF has been shown in randomised trials to reduce hospital admissions and improve quality of life. There is evidence from registry data to suggest it reduces the risk of stroke and improves mortality. Cost effectiveness has been demonstrated by modelling studies in both Europe and the United States.
    Original languageEnglish
    Pages (from-to)395-401
    Number of pages7
    JournalHeart, Lung and Circulation
    Issue number6-7
    Publication statusPublished - 2012


    • Atrial fibrillation
    • Catheter ablation
    • Cost effectiveness
    • Pulmonary vein isolation
    • Pulmonary veins
    • Stroke


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