CellML metadata standards, associated tools and repositories

Daniel A. Beard, Randall Britten, Mike T. Cooling, Alan Garny, Matt D B Halstead, Peter J. Hunter, James Lawson, Catherine M. Lloyd, Justin Marsh, Andrew Miller, David P. Nickerson, Poul M F Nielsen, Taishin Nomura, Shankar Subramanium, Sarala M. Wimalaratne, Tommy Yu

Research output: Contribution to journalArticlepeer-review

54 Citations (Scopus)


The development of standards for encoding mathematical models is an important component of model building and model sharing among scientists interested in understanding multi-scale physiological processes. CellML provides such a standard, particularly for models based on biophysical mechanisms, and a substantial number of models are now available in the CellML Model Repository. However, there is an urgent need to extend the current CellML metadata standard to provide biological and biophysical annotation of the models in order to facilitate model sharing, automated model reduction and connection to biological databases. This paper gives a broad overview of a number of new developments on CellML metadata and provides links to further methodological details available from the CellML website.

Original languageEnglish
Pages (from-to)1845-1867
Number of pages23
JournalPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Issue number1895
Publication statusPublished - 28 May 2009
Externally publishedYes


  • CellML
  • Markup languages
  • Metadata
  • Modelling


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