Central venous pressure: Soon an outcome-Associated matter

Soren Sondergaard*, Geoffrey Parkin, Anders Aneman

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

18 Citations (Scopus)


Purpose of review Central venous pressure (CVP) alone has so far not found a place in outcome prediction or prediction of fluid responsiveness. Improved understanding of the interaction between mean systemic pressure (Pms) and CVP has major implications for evaluating volume responsiveness, heart performance and potentially patient outcomes. Recent findings The literature review substantiates that CVP plays a decisive role in causation of operative haemorrhage and renal failure. The review details CVP as a variable integral to cardiovascular control in its dual role of distending the diastolic right ventricle and opposing venous return. Summary The implication for practice is in the regulation of the circulation. It is demonstrated that control of the blood pressure and cardiac output/venous return calls upon regulation of the volume state (Pms), the heart performance (Eh) and the systemic vascular resistance. Knowledge of the CVP is required to calculate all three.

Original languageEnglish
Pages (from-to)179-185
Number of pages7
JournalCurrent Opinion in Anaesthesiology
Issue number2
Publication statusPublished - Apr 2016
Externally publishedYes


  • cardiovascular regulation
  • central venous pressure
  • heart efficiency
  • venous return
  • volume responsiveness


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