Cerebral tissue oxygen saturation (SrO2) from near infrared spectroscopy (NIRS) measurements following 90°-head-up tilt

A. Martinez-Coll*, M. K. Morgan, P. G. Cooper, H. T. Nguyen, S. N. Hunyor

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Changes in posture from supine to erect (head up) elicit changes in the hydrostatic pressure gradient acting on the systemic cerebral circulation. The initial effect of a headup tilt (HUT) is a decrease in mean arterial pressure and a concomitant temporary decrease in blood flow (Patterson and Warren, 1952) which in turn triggers the appropriate myogenic mechanisms to maintain flow. At the venous end, the same changes in posture result in decreased blood volume.
Original languageEnglish
Pages (from-to)125-131
Number of pages7
JournalAdvances in Experimental Medicine and Biology
Volume471
DOIs
Publication statusPublished - 1999
Externally publishedYes

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