TY - GEN
T1 - Challenges in using clinical data for AI-enabled diagnostic support
AU - Prgomet, Mirela
AU - Kibret, Getiye Dejenu
AU - Thomas, Judith
AU - Loh, Tze Ping
AU - Choy, Kay Weng
AU - Horvath, Andrea
N1 - Copyright the Author(s) 2026. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.
PY - 2026/5/21
Y1 - 2026/5/21
N2 - Secondary use of clinical data for research and algorithm development can present challenges. Using a multi-hospital, retrospective dataset, we examined laboratory values and corresponding recorded diagnoses across common tests. Unanticipated findings prompted further investigation, leading to the identification of key interpretive considerations when using routinely collected clinical data. We highlight three challenges: data quality and completeness; temporality and clinical context; and coding and governance constraints. These challenges have important implications for the development of AI-enabled tools in clinical settings.
AB - Secondary use of clinical data for research and algorithm development can present challenges. Using a multi-hospital, retrospective dataset, we examined laboratory values and corresponding recorded diagnoses across common tests. Unanticipated findings prompted further investigation, leading to the identification of key interpretive considerations when using routinely collected clinical data. We highlight three challenges: data quality and completeness; temporality and clinical context; and coding and governance constraints. These challenges have important implications for the development of AI-enabled tools in clinical settings.
KW - Artificial intelligence
KW - clinical decision support
KW - data quality
KW - pathology
UR - https://www.scopus.com/pages/publications/105039957648
U2 - 10.3233/SHTI260219
DO - 10.3233/SHTI260219
M3 - Conference proceeding contribution
C2 - 42174895
T3 - Studies in Health Technology and Informatics
SP - 514
EP - 515
BT - Opening the Personal Gate between Technology and Health Care
A2 - Giacomini, Mauro
A2 - Delgado, Jaime
A2 - Arvanitis, Theodoros N.
A2 - Andrikopoulou, Elisavet
A2 - Benis, Arriel
A2 - Balestra, Gabriella
A2 - Bellazzi, Riccardo
A2 - Gallos, Parisis
A2 - Gatta, Roberto
A2 - Giacobbe, Daniele Roberto
A2 - Giordano, Noemi
A2 - Hägglund, Maria
A2 - Lindsköld, Lars
A2 - Lhotska, Lenka
A2 - Marceglia, Sara
A2 - Parimbelli, Enea
A2 - Sacchi, Lucia
A2 - Soda, Paolo
A2 - Stoicu-Tivadar, Lăcrămioara
A2 - Veltri, Pierangelo
A2 - Vizza, Patrizia
PB - IOS Press
CY - Amsterdam
T2 - 36th Medical Informatics in Europe Conference, MIE 2026
Y2 - 25 May 2026 through 28 May 2026
ER -