Characterization and optimization of AuNPs labeled by Raman reporters on glass based on silver enhancement

Yuling Wang, Wen Ren, Shaojun Dong*, Erkang Wang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


In this report, gold nanoparticles (AuNPs) labeled by Raman reporters (AuNPs-R6G) were assembled on glass and used as the seeds to in situ grow silver-coated nanostructures based on silver enhancer solution, forming the nanostructures of AuNPs-R6G@Ag, which were characterized by scanning electron microscopy (SEM) and UV-visible spectroscopy. More importantly, the obtained silver-coated nanostructures can be used as a surface enhancement Raman scattering (SERS) substrate. The different SERS activities can be controlled by the silver deposition time and assembly time of AuNPs-R6G on glass. The results indicate that the maximum SERS activity could be obtained on AuNPs-R6G when these nanostructures were assembled on glass for 2 h with silver deposition for 2 min. In addition, the reproducibility of SERS signal on the fabricated nanostructures is very high with the intensity error lower than 15%, which has great promise as a probe for application in bioanalysis.

Original languageEnglish
Pages (from-to)571-576
Number of pages6
JournalJournal of Raman Spectroscopy
Issue number5
Publication statusPublished - May 2009
Externally publishedYes


  • Gold nanoparticles
  • Raman reporter
  • Rhodamine 6G
  • SERS
  • Silver enhancement


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