Chemical sensing with nanoparticles as optical reporters: From noble metal nanoparticles to quantum dots and upconverting nanoparticles

Research output: Contribution to journalReview articleResearch

Abstract

A wide variety of biological and medical analyses are based on the use of optical signals to report specific molecular events. Thanks to advances in nanotechnology, various nanostructures have been extensively used as optical reporters in bio- and chemical assays. This review describes recent progress in chemical sensing using noble metal nanoparticles (gold and silver), quantum dots and upconverting nanoparticles. It provides insights into various nanoparticle-based sensing strategies including fluorescence/luminescence resonance energy transfer nanoprobes as well as activatable probes sensitive to specific changes in the biological environment. Finally we list some research challenges to be overcome in order to accelerate the development of applications of nanoparticle bio- and chemical sensors.

LanguageEnglish
Pages5321-5334
Number of pages14
JournalAnalyst
Volume139
Issue number21
DOIs
Publication statusPublished - 2014

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Metal Nanoparticles
Quantum Dots
Metal nanoparticles
Precious metals
Nanoparticles
Semiconductor quantum dots
metal
Nanoprobes
Fluorescence Resonance Energy Transfer
Nanotechnology
Nanostructures
Luminescence
Chemical sensors
Silver
Gold
Energy transfer
nanotechnology
Assays
luminescence
Fluorescence

Cite this

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abstract = "A wide variety of biological and medical analyses are based on the use of optical signals to report specific molecular events. Thanks to advances in nanotechnology, various nanostructures have been extensively used as optical reporters in bio- and chemical assays. This review describes recent progress in chemical sensing using noble metal nanoparticles (gold and silver), quantum dots and upconverting nanoparticles. It provides insights into various nanoparticle-based sensing strategies including fluorescence/luminescence resonance energy transfer nanoprobes as well as activatable probes sensitive to specific changes in the biological environment. Finally we list some research challenges to be overcome in order to accelerate the development of applications of nanoparticle bio- and chemical sensors.",
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Chemical sensing with nanoparticles as optical reporters : From noble metal nanoparticles to quantum dots and upconverting nanoparticles. / Deng, Wei; Goldys, Ewa M.

In: Analyst, Vol. 139, No. 21, 2014, p. 5321-5334.

Research output: Contribution to journalReview articleResearch

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