Chemotactic Responses of Tunicate (Urochordata, Ascidiacea) Hemocytesin Vitro

David A. Raftos; Dan L. Stillman; Edwin L. Cooper

doi:10.1006/jipa.1998.4760

Chemotactic Responses of Tunicate (Urochordata, Ascidiacea) Hemocytesin Vitro

David A. Raftos^*, Dan L. Stillman, Edwin L. Cooper

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

A number of molecules were found to alter the motility of tunicate hemocytes. Bacterial lipopolysaccharide (LPS) significantly enhanced cell mobility relative to non-stimulated controls. Responses to LPS were not directional and so represented chemokinesis. In contrast, checkerboard analyses indicated that two tunicate hemolymph proteins, tunIL1-α and -β, stimulated truly directional chemotaxis by hemocytes. The data suggest that tunIL1 proteins may contribute to defense by altering the localization of immunocompetent cells.

Original language	English
Pages (from-to)	44-49
Number of pages	6
Journal	Journal of Invertebrate Pathology
Volume	72
Issue number	1
DOIs	https://doi.org/10.1006/jipa.1998.4760
Publication status	Published - Jul 1998

Keywords

Tunicate; ascidian; chemotaxis; chemoattraction; chemokinesis.

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10.1006/jipa.1998.4760

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abstract = "A number of molecules were found to alter the motility of tunicate hemocytes. Bacterial lipopolysaccharide (LPS) significantly enhanced cell mobility relative to non-stimulated controls. Responses to LPS were not directional and so represented chemokinesis. In contrast, checkerboard analyses indicated that two tunicate hemolymph proteins, tunIL1-α and -β, stimulated truly directional chemotaxis by hemocytes. The data suggest that tunIL1 proteins may contribute to defense by altering the localization of immunocompetent cells.",

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Chemotactic Responses of Tunicate (Urochordata, Ascidiacea) Hemocytesin Vitro

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Keywords

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