Chemotactic Responses of Tunicate (Urochordata, Ascidiacea) Hemocytesin Vitro

David A. Raftos*, Dan L. Stillman, Edwin L. Cooper

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    22 Citations (Scopus)


    A number of molecules were found to alter the motility of tunicate hemocytes. Bacterial lipopolysaccharide (LPS) significantly enhanced cell mobility relative to non-stimulated controls. Responses to LPS were not directional and so represented chemokinesis. In contrast, checkerboard analyses indicated that two tunicate hemolymph proteins, tunIL1-α and -β, stimulated truly directional chemotaxis by hemocytes. The data suggest that tunIL1 proteins may contribute to defense by altering the localization of immunocompetent cells.

    Original languageEnglish
    Pages (from-to)44-49
    Number of pages6
    JournalJournal of Invertebrate Pathology
    Issue number1
    Publication statusPublished - Jul 1998


    • Tunicate; ascidian; chemotaxis; chemoattraction; chemokinesis.


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