TY - JOUR
T1 - Chiral metal complexes. 6. The kinetically controlled stereoselective synthesis of ternary Co(III) complexes of the type [Co(phen)2(S-aminoacidate)]n+
AU - Chambers, Jill A.
AU - Gillard, Robert D.
AU - Williams, Peter A.
AU - Vagg, Robert S.
PY - 1983
Y1 - 1983
N2 - The complexes Λ[Co(phen)2(aa)]2+, where aa is the singly charged anion of the α-amino acids S-glutamine, S-asparagine, S-glutamic acid and S-aspartic acid, and phen is 1,10-phenanthroline, may be synthesized stereospecifically under certain conditions by the reaction of the amino acid with Δ,Λ[Co(phen)2CO3]+. Kinetic, rather than thermodynamic, influences are responsible for the reaction products observed. It is evident that both diastereoisomers of the bis-phen complex form initially, but the rate of decomposition of the Δ-isomer is considerably faster than that of the Λ-isomer. The results have been used to reinterpret some earlier work on chiral discriminations in related complexes containing 1,2-diaminoethane, and recent results concerning the phen complexes containing glycine, S-alanine, S-phenylalanine, S-leucine, S-isoleucine and S-valine.
AB - The complexes Λ[Co(phen)2(aa)]2+, where aa is the singly charged anion of the α-amino acids S-glutamine, S-asparagine, S-glutamic acid and S-aspartic acid, and phen is 1,10-phenanthroline, may be synthesized stereospecifically under certain conditions by the reaction of the amino acid with Δ,Λ[Co(phen)2CO3]+. Kinetic, rather than thermodynamic, influences are responsible for the reaction products observed. It is evident that both diastereoisomers of the bis-phen complex form initially, but the rate of decomposition of the Δ-isomer is considerably faster than that of the Λ-isomer. The results have been used to reinterpret some earlier work on chiral discriminations in related complexes containing 1,2-diaminoethane, and recent results concerning the phen complexes containing glycine, S-alanine, S-phenylalanine, S-leucine, S-isoleucine and S-valine.
UR - http://www.scopus.com/inward/record.url?scp=0010303367&partnerID=8YFLogxK
U2 - 10.1016/S0020-1693(00)82797-8
DO - 10.1016/S0020-1693(00)82797-8
M3 - Article
AN - SCOPUS:0010303367
SN - 0020-1693
VL - 70
SP - 167
EP - 173
JO - Inorganica Chimica Acta
JF - Inorganica Chimica Acta
IS - C
ER -