Abstract
Chronic exposure to inorganic arsenic in drinking water has been associated with Type 2 Diabetes (T2D). However, the association is still inconclusive. We incorporated 33 studies in the analysis including 13 cross-sectional, 6 case-control and 4 cohort studies reporting Odds Ratio (OR), 6 cross-sectional and cohort studies reporting Relative Risk (RR) and 3 mortality studies reporting Standardized Mortality Ratio (SMR). The pooled OR estimate was 1.76 (95% CI: 1.43, 2.17), pooled RR was 1.17 (95% CI: 0.95, 1.45) and pooled SMR was 0.79 (95% CI: 0.59, 1.06), and the overall pooled estimate was 1.55 (95% CI: 1.27, 1.88). The study heterogeneity was very high (I2 = 97% for case-control studies, 47% for cohort studies, and overall 98%). Because of the very high heterogeneity and non-significant results from cohort studies, this analysis provides a limited evidence for an association between arsenic and Type 2 Diabetes (T2D) that needs further validation.
| Original language | English |
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| Title of host publication | One Century of the Discovery of Arsenicosis in Latin America (1914-2014) |
| Subtitle of host publication | As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment |
| Place of Publication | Argentina |
| Publisher | CRC Press/Balkema |
| Pages | 590-591 |
| Number of pages | 2 |
| ISBN (Print) | 9781138001411 |
| Publication status | Published - 2014 |
| Externally published | Yes |
| Event | 5th International Congress on Arsenic in the Environment, As 2014 - Buenos Aires, Argentina Duration: 11 May 2014 → 16 May 2014 |
Other
| Other | 5th International Congress on Arsenic in the Environment, As 2014 |
|---|---|
| Country/Territory | Argentina |
| City | Buenos Aires |
| Period | 11/05/14 → 16/05/14 |