Circuit impedance could be a crucial factor influencing radiofrequency ablation efficacy and safety: a myocardial phantom study of the problem and its correction

Abhishek Bhaskaran, M. A. Barry, Jim Pouliopoulos, Chrishan Nalliah, Pierre Qian, William Chik, Sujitha Thavapalachandran, Lloyd Davis, Alistair McEwan, Stuart Thomas, Pramesh Kovoor, Aravinda Thiagalingam

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Background: Circuit impedance could affect the safety and efficacy of radiofrequency (RF) ablation.

Aim: To perform irrigated RF ablations with graded impedance to compare (1) lesion dimensions and overheated dimensions in fixed power ablations (2) and in power corrected ablations.

Methods: Ablations were performed with irrigated Navistar Thermocool catheter and Stockert EP shuttle generator at settings of 40 W power for 60 seconds, in a previously validated myocardial phantom. The impedance of the circuit was set at 60 Ω, 80 Ω, 100 Ω, 120 Ω, 140 Ω, and 160 Ω. The lesion and overheated dimensions were measured at 53 °C and 80 °C isotherms, respectively. In the second set of ablations, power was corrected according to circuit impedance.

Results: In total, 70 ablations were performed. The lesion volume was 72.0 ± 4.8% and 44.7 ± 4.6% higher at 80 Ω and 100 Ω, respectively, compared to that at 120 Ω and it was 15.4 ± 1.2%, 28.1 ± 2.0%, and 38.0 ± 1.8% lower at 140 Ω, 160 Ω, and 180 Ω, respectively. The overheated volume was four times larger when impedance was reduced to 80 Ω from 100 Ω. It was absent at 120 Ω and above. In the power corrected ablations, the lesion volumes were similar to that of 40 W/120 Ω ablations and there was no evidence of overheating.

Conclusion: The lesion and overheated dimensions were significantly larger with lower circuit impedance during irrigated RF ablation and the lesion size was smaller in high impedance ablations. Power delivery adjusted to impedance using a simple equation improved the consistency of lesion formation and prevented overheating.

Original languageEnglish
Pages (from-to)351-357
Number of pages7
JournalJournal of Cardiovascular Electrophysiology
Volume27
Issue number3
DOIs
Publication statusPublished - Mar 2016
Externally publishedYes

Keywords

  • circuit impedance
  • lesion dimensions
  • myocardial phantom
  • radiofrequency ablation
  • safety

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