Circular dichroism and related spectroscopic techniques

Sophia C. Goodchild, Krishanthi Jayasundera, Alison Rodger

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


    Circular dichroism (CD) is an absorption spectroscopy technique that is uniquely sensitive to the helical nature of transitions. It can therefore be used to provide qualitative and quantitative information about any chiral molecule that has an absorption spectrum in the wavelength region of interest. Applications of ultraviolet circular dichroism spectroscopy to study protein secondary structure represent the current predominant applications. Vibrational circular dichroism is seeing increasing application, particularly in the study of small molecules. Related techniques that can be used to extract structural information on solutions of molecules include linear dichroism and infra‐red absorbance spectroscopies.
    Original languageEnglish
    Title of host publicationBiomolecular and bioanalytical techniques
    Subtitle of host publicationtheory, methodology and applications
    EditorsVasudevan Ramesh
    Place of PublicationHoboken, USA
    Number of pages20
    ISBN (Electronic)9781119483984, 9781119484011
    ISBN (Print)9781119483960
    Publication statusPublished - 2019


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