Clinical aspects of Alzheimer’s disease

Fiona Kumfor*, Glenda M. Halliday, Olivier Piguet

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

4 Citations (Scopus)

Abstract

Alzheimer’s disease is the most common form of dementia accounting for 50–60% of all dementia cases. This chapter briefly reviews the history of Alzheimer’s disease and provides an overview of the clinical syndromes associated with Alzheimer pathology and their associated neuroimaging findings. This chapter also reviews the neuropathology and genetics of Alzheimer’s disease and concludes by discussing current work undertaken to identify suitable in vivo biomarkers for the disease.

Original languageEnglish
Title of host publicationNeurodegenerative diseases
Subtitle of host publicationpathology, mechanisms, and potential therapeutic targets
EditorsPhilip Beart, Michael Robinson, Marcus Rattray, Nicholas J. Maragakis
Place of PublicationCham, Switzerland
PublisherSpringer, Springer Nature
Pages31-53
Number of pages23
ISBN (Electronic)9783319571935
ISBN (Print)9783319571911
DOIs
Publication statusPublished - 2017
Externally publishedYes

Publication series

NameAdvances in Neurobiology
Volume15
ISSN (Print)2190-5215
ISSN (Electronic)2190-5223

Keywords

  • biomarkers
  • cognition
  • genes
  • logopenic progressive aphasia
  • memory
  • neuroimaging
  • posterior cortical atrophy

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