Clinical symptoms predict concurrent social and global functioning in an early psychosis sample

Cristina Cacciotti-Saija, Robyn Langdon, Philip B. Ward, Ian B. Hickie, Adam J. Guastella*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    11 Citations (Scopus)


    Aim: Although well established in chronic schizophrenia, the key determinants of functioning remain unknown during the early phase of a psychotic disorder. The aim of this study was to comprehensively examine the social cognitive, basic neurocognitive and clinical predictors of concurrent social functioning and global functioning in an early psychosis sample.

    Methods: This study examined the relationship between social cognition, basic neurocognition and clinical symptoms with concurrent functioning in 51 early psychosis individuals. Assessments included a range of self-report, observational and clinician-rated measures of cognitive, symptom severity and functioning domains.

    Results: Results revealed a significant association between self-reported social function and lower levels of both social interaction anxiety and negative psychotic symptoms. A significant association was also observed between lower levels of negative psychotic symptoms and observed social functioning. Lastly, results demonstrated a significant association between reduced negative psychotic symptoms and clinician-rated global functioning.

    Conclusions: Clinical domains such as negative symptoms and social interaction anxiety significantly contribute to an optimal model predicting outcome during the early phase of a psychotic disorder. These clinical features may also provide useful markers of an individual's capacity for social participation. Clinical implications include the need for early targeted intervention to address social anxiety and negative psychotic symptoms to facilitate optimum patient outcome.

    Original languageEnglish
    Pages (from-to)177-184
    Number of pages8
    JournalEarly Intervention in Psychiatry
    Issue number2
    Early online date2 Dec 2015
    Publication statusPublished - 1 Apr 2018


    • clinical symptom
    • schizophrenia
    • social cognition
    • social functioning
    • first-episode psychosis


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