CMKb: a web-based prototype for integrating Australian Aboriginal customary medicinal plant knowledge

Jitendra Gaikwad, Varun Khanna, Subramanyam Vemulpad, Joanne Jamie, Jim Kohen, Shoba Ranganathan

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background: The customary medicinal plant knowledge possessed by the Australian Aboriginal people is a significant resource. Published information on it is scattered throughout the literature, in heterogeneous data formats, and is scattered among various Aboriginal communities across Australia, due to a multiplicity of languages. This ancient knowledge is at risk due to loss of biodiversity, cultural impact and the demise of many of its custodians. We have developed the Customary Medicinal Knowledgebase (CMKb), an integrated multidisciplinary resource, to document, conserve and disseminate this knowledge. Description: CMKb is an online relational database for collating, disseminating, visualising and analysing initially public domain data on customary medicinal plants. The database stores information related to taxonomy, phytochemistry, biogeography, biological activities of customary medicinal plant species as well as images of individual species. The database can be accessed at http://biolinfo.org/cmkb. Known bioactive molecules are characterized within the chemoinformatics module of CMKb, with functions available for molecular editing and visualization. Conclusion: CMKb has been developed as a prototype data resource for documenting, integrating, disseminating, analysing multidisciplinary customary medicinal plant data from Australia and to facilitate user-defined complex querying. Each species in CMKb is linked to online resources such as the Integrated Taxonomic Information System (ITIS), NCBI Taxonomy, Australia's SpeciesLinks-Integrated Botanical Information System (IBIS) and Google images. The bioactive compounds are linked to the PubChem database. Overall, CMKb serves as a single knowledgebase for holistic plant-derived therapeutics and can be used as an information resource for biodiversity conservation, to lead discovery and conservation of customary medicinal knowledge.

LanguageEnglish
Article numberS25
Pages1-8
Number of pages8
JournalBMC Bioinformatics
Volume9
Issue numberSUPPL. 12
DOIs
Publication statusPublished - 12 Dec 2008

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Knowledge Bases
Medicinal Plants
prototypes
Knowledge Base
Web-based
medicinal plants
Prototype
Biodiversity
information systems
Taxonomies
Resources
Conservation
Databases
Information systems
biodiversity
taxonomy
Integrated System
plant biochemistry
indigenous peoples
Taxonomy

Cite this

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title = "CMKb: a web-based prototype for integrating Australian Aboriginal customary medicinal plant knowledge",
abstract = "Background: The customary medicinal plant knowledge possessed by the Australian Aboriginal people is a significant resource. Published information on it is scattered throughout the literature, in heterogeneous data formats, and is scattered among various Aboriginal communities across Australia, due to a multiplicity of languages. This ancient knowledge is at risk due to loss of biodiversity, cultural impact and the demise of many of its custodians. We have developed the Customary Medicinal Knowledgebase (CMKb), an integrated multidisciplinary resource, to document, conserve and disseminate this knowledge. Description: CMKb is an online relational database for collating, disseminating, visualising and analysing initially public domain data on customary medicinal plants. The database stores information related to taxonomy, phytochemistry, biogeography, biological activities of customary medicinal plant species as well as images of individual species. The database can be accessed at http://biolinfo.org/cmkb. Known bioactive molecules are characterized within the chemoinformatics module of CMKb, with functions available for molecular editing and visualization. Conclusion: CMKb has been developed as a prototype data resource for documenting, integrating, disseminating, analysing multidisciplinary customary medicinal plant data from Australia and to facilitate user-defined complex querying. Each species in CMKb is linked to online resources such as the Integrated Taxonomic Information System (ITIS), NCBI Taxonomy, Australia's SpeciesLinks-Integrated Botanical Information System (IBIS) and Google images. The bioactive compounds are linked to the PubChem database. Overall, CMKb serves as a single knowledgebase for holistic plant-derived therapeutics and can be used as an information resource for biodiversity conservation, to lead discovery and conservation of customary medicinal knowledge.",
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CMKb : a web-based prototype for integrating Australian Aboriginal customary medicinal plant knowledge. / Gaikwad, Jitendra; Khanna, Varun; Vemulpad, Subramanyam; Jamie, Joanne; Kohen, Jim; Ranganathan, Shoba.

In: BMC Bioinformatics, Vol. 9, No. SUPPL. 12, S25, 12.12.2008, p. 1-8.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Khanna, Varun

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AU - Jamie, Joanne

AU - Kohen, Jim

AU - Ranganathan, Shoba

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