Collection and normal levels of the amyloid precursor protein in plasma

Scott Whyte, Neil Wilson, Jon Currie, Paul Maruff, Valencia Malone, Ruxsana Shafiq-Antonacci, Peter Tyler, Kathryn L. Derry, John Underwood, Qiao-Xin Li, Konrad Beyreuther, Colin L. Masters, Stephanie J. Fuller (Contributor)

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


The amyloid precursor protein is contained in plantelet alpha granules and released with degranulation. Methods are described to control for amyloid precursor protein release from platelets during blood collection and processing. In normal subjects (n = 97; age range, 44–84 years), the average plasma level of amyloid precursor protein was 6.5 ± 1.8 ng/ml.
Original languageEnglish
Pages (from-to)121-124
Number of pages4
JournalAnnals of Neurology
Issue number1
Publication statusPublished - 1997
Externally publishedYes


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