@inbook{2884c8e4182d4a4fa17740f9b2f4936a,
title = "Comparative genomic analysis of glycoylation pathways in yeast, plants and higher eukaryotes",
abstract = "N-linked glycosylation is an essential modification of secretory and membrane proteins in all eukaryotic cells. Here, we review the current metabolic pathways of N-linked oligosaccharide biosynthesis in the endoplasmic reticulum and in the Golgi apparatus for yeasts: Saccharomyces cerevisiae and Schizosaccharomyces pombe, and higher eukaryotes: plants and human. The evolutionarily conserved proteins, processed in the cytosolic and the luminal side of the ER membrane, and the unique genes and their specific functions, occurring in the Golgi complex, for each selected organism, will be collated and discussed. This precise knowledge of the glycosylation pathway contributes to better understanding of the N-linked glycoprotein biosynthesis among different species, resulting in the recently successfully engineered strains for heterologous gene expression systems for industrial and therapeutic protein production.",
author = "Shoba Ranganathan and Sangdao Wongsai and {Helena Nevalainen}, {K. M.}",
year = "2006",
doi = "10.1016/S1874-5334(06)80013-4",
language = "English",
isbn = "9780444518071",
volume = "6",
series = "Applied mycology and biotechnology",
publisher = "Elsevier",
pages = "227--248",
editor = "Arora, {Dilip K.} and Berka, {Randy M.} and Singh, {Gautam B.}",
booktitle = "Bioinformatics",
address = "Netherlands",
}