Comparison of live rat femoral artery model with intraoperative microvascular anastomosis

Mark V. Schaverien*, Charles E. Butler, Hiroo Suami, Jun Liu, Jesse C. Selber

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    2 Citations (Scopus)


    Background: The live rat femoral artery model is the gold standard in high-fidelity simulation for microvascular anastomosis worldwide. Despite widespread use, there is a paucity of evidence for its validity. This study aims to determine the correlation between microvascular anastomosis in the live rat femoral artery model and clinical performance. 

    Methods: Twenty-nine microsurgical fellows were included in the study. At the beginning and end of the 1-year fellowship, fellows were assessed performing arterial microvascular anastomoses in the laboratory in a live rat femoral artery model. Each procedure was digitally video recorded and blinded. Fellows were also assessed in the operating room at the beginning and end of training performing microvascular anastomoses in multiple free flap cases. Validated tools were used for assessment, and duration of procedure was also recorded. The results from the evaluations were compared and interfellow comparisons were performed. 

    Results: At both the beginning and end of the fellowship, there was no significant correlation between clinical performance evaluations during operating room cases and laboratory evaluations. In the laboratory, higher performance scores were associated with faster times at both the beginning and end of the fellowship. 

    Conclusion: Contrary to conventional wisdom, microsurgical skill in the live rat femoral artery model in the laboratory does not correlate with clinical performance in the operating room. This calls into question the utility of this model for training purposes. Further research is necessary to corroborate these results and potentially establish experimental models with greater validity and reliability.

    Original languageEnglish
    Pages (from-to)641-648
    Number of pages8
    JournalJournal of Reconstructive Microsurgery
    Issue number9
    Publication statusPublished - 2017


    • comparison
    • fellow
    • intraoperative evaluation
    • microsurgery
    • rat model


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