Comparison of low-dose coronary artery calcium scoring using low tube current technique and hybrid iterative reconstruction vs. filtered back projection

Nada Sulaiman, Jeanette Soon, Jong kwan Park, Christopher Naoum, Shaw Hua Kueh, Philipp Blanke, Darra Murphy, Jennifer Ellis, Cameron J. Hague, Jonathon Leipsic*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Introduction We sought to validate whether low dose CACS CT with hybrid IR (HIR) could replace standard dose filtered back projection (FBP). Method We enrolled 100 patients to undergo low dose CACS CT with HIR, in addition to routine full dose FBP. Results No significant difference between full and low dose CT in Agatston score 138.2 ± 360.6 vs. 137.3 ± 356.4 (p = 0.272) or calcium mass score 19 ± 48.3 vs. 18.7 ± 49 (p = 0.8), respectively. Bland–Altman analysis showed no systematic bias. Calcium volume difference was statistically significant 57.2 ± 134 vs. 55.1 ± 130.2 (p = 0.001). Conclusion Low dose CT for calcium scoring with HIR enables stable CACS Agatston score and calcium mass quantification as compared to full dose FBP.

Original languageEnglish
Pages (from-to)19-23
Number of pages5
JournalClinical Imaging
Volume43
DOIs
Publication statusPublished - May 2017
Externally publishedYes

Keywords

  • coronary artery calcium score
  • computed tomography
  • iterative reconstruction
  • filtered back projection
  • noise index
  • Agatston score

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