Comparison of mandibular advancement splint and tongue stabilizing device in obstructive sleep apnea: A randomized controlled trial

Sheryn A. Deane, Peter A. Cistulli, Andrew T. Ng, Biao Zeng, Peter Petocz, M. Ali Darendeliler

    Research output: Contribution to journalArticlepeer-review

    80 Citations (Scopus)

    Abstract

    Study Objectives: To compare the efficacy of a mandibular advancement splint (MAS) and a novel tongue stabilizing device (TSD) in the treatment of obstructive sleep apnea (OSA). Design: A randomized crossover design was used. Patients: Twenty-seven patients (20 male, 7 female), recruited from a tertiary hospital sleep clinic. Measurements and Results: The apnea-hypopnea index (AHI) was reduced with MAS (11.68 ± 8.94, P = 0.000) and TSD (13.15 ± 10.77, P = 0.002) compared with baseline (26.96 ± 17.17). The arousal index decreased for MAS (21.09 ± 9.27, P = 0.004) and TSD (21.9 ± 10.56, P = 0.001) compared with baseline (33.23 ± 16.41). Sixty-eight percent of patients achieved a complete or partial response with MAS, compared with 45% with TSD. The Epworth Sleepiness Scale (ESS) score was decreased with MAS (P = <0.001) and TSD (P = 0.002). Subjective improvements in snoring and quality of sleep were reported, with a better response for MAS than TSD. Compliance was poorer for TSD, and the side effect profiles of the 2 modalities were different. All patients were satisfied with MAS compared to TSD, and 91% of patients preferred the MAS. Conclusion: Objective testing showed the MAS and TSD had similar efficacy in terms of AHI reduction. Patients reported improvements with both devices; however, better compliance and a clear preference for MAS was apparent when both devices were offered. Longer term studies are needed to clarify the role of TSD.

    Original languageEnglish
    Pages (from-to)648-653
    Number of pages6
    JournalSleep
    Volume32
    Issue number5
    Publication statusPublished - 1 May 2009

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