Comparison of the pressor effects of angiotensin II and III in the rostral ventrolateral medulla

S. Sasaki; Y. W. Li; R. A L Dampney

doi:10.1016/0006-8993(93)91393-7

Comparison of the pressor effects of angiotensin II and III in the rostral ventrolateral medulla

S. Sasaki, Y. W. Li, R. A L Dampney^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Microinjection of angiotensin II and III into the rostral ventrolateral medulla of anesthetized barodenervated rabbits elicited in both cases pressor responses, which were of similar magnitude and time course. The responses to angiotensin II and III were either unchanged or increased in the presence of compounds which inhibit their degradation to shorter length peptides. The results indicate that both angiotensin peptides are independently capable of eliciting pressor responses in the rostral ventrolteral medulla.

Original language	English
Pages (from-to)	335-338
Number of pages	4
Journal	Brain Research
Volume	600
Issue number	2
DOIs	https://doi.org/10.1016/0006-8993(93)91393-7
Publication status	Published - 15 Jan 1993
Externally published	Yes

Keywords

Amastatin
Angiotensin
Bestatin
Blood pressure
Rostral ventrolateral medulla

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10.1016/0006-8993(93)91393-7

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abstract = "Microinjection of angiotensin II and III into the rostral ventrolateral medulla of anesthetized barodenervated rabbits elicited in both cases pressor responses, which were of similar magnitude and time course. The responses to angiotensin II and III were either unchanged or increased in the presence of compounds which inhibit their degradation to shorter length peptides. The results indicate that both angiotensin peptides are independently capable of eliciting pressor responses in the rostral ventrolteral medulla.",

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AU - Dampney, R. A L

PY - 1993/1/15

Y1 - 1993/1/15

N2 - Microinjection of angiotensin II and III into the rostral ventrolateral medulla of anesthetized barodenervated rabbits elicited in both cases pressor responses, which were of similar magnitude and time course. The responses to angiotensin II and III were either unchanged or increased in the presence of compounds which inhibit their degradation to shorter length peptides. The results indicate that both angiotensin peptides are independently capable of eliciting pressor responses in the rostral ventrolteral medulla.

AB - Microinjection of angiotensin II and III into the rostral ventrolateral medulla of anesthetized barodenervated rabbits elicited in both cases pressor responses, which were of similar magnitude and time course. The responses to angiotensin II and III were either unchanged or increased in the presence of compounds which inhibit their degradation to shorter length peptides. The results indicate that both angiotensin peptides are independently capable of eliciting pressor responses in the rostral ventrolteral medulla.

KW - Amastatin

KW - Angiotensin

KW - Bestatin

KW - Blood pressure

KW - Rostral ventrolateral medulla

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ER -

Comparison of the pressor effects of angiotensin II and III in the rostral ventrolateral medulla

Abstract

Keywords

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