Complete partial volume solution for ASL brain perfusion data applied to relapse remitting multiple sclerosis patients

Ruth Oliver; Linda Ly; Chenyu Wang; Heidi Beadnall; Ilaria Boscolo Galazzo; Michael Chappell; Xavier Golay; Enrico De Vita; David Thomas; Michael Barnett

Complete partial volume solution for ASL brain perfusion data applied to relapse remitting multiple sclerosis patients

Ruth Oliver, Linda Ly, Chenyu Wang, Heidi Beadnall, Ilaria Boscolo Galazzo, Michael Chappell, Xavier Golay, Enrico De Vita, David Thomas, Michael Barnett

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution

Abstract

ASL is a low resolution imaging modality that suffers from the partial volume effect, leading to an underestimation of GM perfusion. This effect has two principle causes; blurring from the point spread function in the slice direction, and inadequate resolution due to the need for large voxels to achieve sufficient SNR. Both may act as confounders for measurement of GM CBF abnormalities. Decreased GM perfusion could reflect neuronal loss or metabolic dysfunction; PV correction allows a decoupling of structure and function. We present the first application of a complete PV correction solution for ASL to a cohort of MS patients.

Original language	English
Title of host publication	24th ISMRM annual meeting and exhibition 2016 and 25th SMRT annual meeting 2016
Subtitle of host publication	proceedings
Place of Publication	Concord, CA
Publisher	International Society for Magnetic Resonance in Medicine
Pages	6804-6806
Number of pages	3
Volume	13
ISBN (Print)	9781510837683
Publication status	Published - 2017
Externally published	Yes
Event	ISMRM 24th Annual Meeting and Exhibition (2016) - , Singapore Duration: 7 May 2016 → 13 May 2016 Conference number: 24th

Conference

Conference	ISMRM 24th Annual Meeting and Exhibition (2016)
Country/Territory	Singapore
Period	7/05/16 → 13/05/16

Cite this

Oliver, R., Ly, L., Wang, C., Beadnall, H., Boscolo Galazzo, I., Chappell, M., Golay, X., De Vita, E., Thomas, D., & Barnett, M. (2017). Complete partial volume solution for ASL brain perfusion data applied to relapse remitting multiple sclerosis patients. In 24th ISMRM annual meeting and exhibition 2016 and 25th SMRT annual meeting 2016: proceedings (Vol. 13, pp. 6804-6806). International Society for Magnetic Resonance in Medicine.

@inproceedings{688864bfd82d4fec9f8e5922618ac276,

title = "Complete partial volume solution for ASL brain perfusion data applied to relapse remitting multiple sclerosis patients",

abstract = "ASL is a low resolution imaging modality that suffers from the partial volume effect, leading to an underestimation of GM perfusion. This effect has two principle causes; blurring from the point spread function in the slice direction, and inadequate resolution due to the need for large voxels to achieve sufficient SNR. Both may act as confounders for measurement of GM CBF abnormalities. Decreased GM perfusion could reflect neuronal loss or metabolic dysfunction; PV correction allows a decoupling of structure and function. We present the first application of a complete PV correction solution for ASL to a cohort of MS patients.",

author = "Ruth Oliver and Linda Ly and Chenyu Wang and Heidi Beadnall and {Boscolo Galazzo}, Ilaria and Michael Chappell and Xavier Golay and {De Vita}, Enrico and David Thomas and Michael Barnett",

year = "2017",

language = "English",

isbn = "9781510837683",

volume = "13",

pages = "6804--6806",

booktitle = "24th ISMRM annual meeting and exhibition 2016 and 25th SMRT annual meeting 2016",

publisher = "International Society for Magnetic Resonance in Medicine",

note = "ISMRM 24th Annual Meeting and Exhibition (2016) ; Conference date: 07-05-2016 Through 13-05-2016",

}

Oliver, R, Ly, L, Wang, C, Beadnall, H, Boscolo Galazzo, I, Chappell, M, Golay, X, De Vita, E, Thomas, D & Barnett, M 2017, Complete partial volume solution for ASL brain perfusion data applied to relapse remitting multiple sclerosis patients. in 24th ISMRM annual meeting and exhibition 2016 and 25th SMRT annual meeting 2016: proceedings. vol. 13, International Society for Magnetic Resonance in Medicine, Concord, CA, pp. 6804-6806, ISMRM 24th Annual Meeting and Exhibition (2016), Singapore, 7/05/16.

Complete partial volume solution for ASL brain perfusion data applied to relapse remitting multiple sclerosis patients. / Oliver, Ruth; Ly, Linda; Wang, Chenyu et al.
24th ISMRM annual meeting and exhibition 2016 and 25th SMRT annual meeting 2016: proceedings. Vol. 13 Concord, CA: International Society for Magnetic Resonance in Medicine, 2017. p. 6804-6806.

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution

TY - GEN

T1 - Complete partial volume solution for ASL brain perfusion data applied to relapse remitting multiple sclerosis patients

AU - Oliver, Ruth

AU - Ly, Linda

AU - Wang, Chenyu

AU - Beadnall, Heidi

AU - Boscolo Galazzo, Ilaria

AU - Chappell, Michael

AU - Golay, Xavier

AU - De Vita, Enrico

AU - Thomas, David

AU - Barnett, Michael

N1 - Conference code: 24th

PY - 2017

Y1 - 2017

N2 - ASL is a low resolution imaging modality that suffers from the partial volume effect, leading to an underestimation of GM perfusion. This effect has two principle causes; blurring from the point spread function in the slice direction, and inadequate resolution due to the need for large voxels to achieve sufficient SNR. Both may act as confounders for measurement of GM CBF abnormalities. Decreased GM perfusion could reflect neuronal loss or metabolic dysfunction; PV correction allows a decoupling of structure and function. We present the first application of a complete PV correction solution for ASL to a cohort of MS patients.

AB - ASL is a low resolution imaging modality that suffers from the partial volume effect, leading to an underestimation of GM perfusion. This effect has two principle causes; blurring from the point spread function in the slice direction, and inadequate resolution due to the need for large voxels to achieve sufficient SNR. Both may act as confounders for measurement of GM CBF abnormalities. Decreased GM perfusion could reflect neuronal loss or metabolic dysfunction; PV correction allows a decoupling of structure and function. We present the first application of a complete PV correction solution for ASL to a cohort of MS patients.

UR - http://www.ismrm.org/2016-annual-meeting-exhibition/

M3 - Conference proceeding contribution

SN - 9781510837683

VL - 13

SP - 6804

EP - 6806

BT - 24th ISMRM annual meeting and exhibition 2016 and 25th SMRT annual meeting 2016

PB - International Society for Magnetic Resonance in Medicine

CY - Concord, CA

T2 - ISMRM 24th Annual Meeting and Exhibition (2016)

Y2 - 7 May 2016 through 13 May 2016

ER -

Oliver R, Ly L, Wang C, Beadnall H, Boscolo Galazzo I, Chappell M et al. Complete partial volume solution for ASL brain perfusion data applied to relapse remitting multiple sclerosis patients. In 24th ISMRM annual meeting and exhibition 2016 and 25th SMRT annual meeting 2016: proceedings. Vol. 13. Concord, CA: International Society for Magnetic Resonance in Medicine. 2017. p. 6804-6806

Complete partial volume solution for ASL brain perfusion data applied to relapse remitting multiple sclerosis patients

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