Consensus document for invasive coronary physiologic assessment in Asia-Pacific countries

Hak Seung Lee, Joo Myung Lee, Chang Wook Nam, Eun Seok Shin, Joon Hyung Doh, Neng Dai, Martin K. C. Ng, Andy S. C. Yong, Damras Tresukosol, Ajit S. Mullasari, Rony Mathew, Praveen Chandra, Kuang Te Wang, Yundai Chen, Jiyan Chen, Kai Hang Yiu, Nils P. Johnson, Bon Kwon Koo

Research output: Contribution to journalArticlepeer-review

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Background: Currently, invasive physiologic assessment such as fractional flow reserve is widely used worldwide with different adoption rates around the globe. Patient characteristics and physician preferences often differ in the Asia-Pacific (APAC) region with respect to treatment strategy, techniques, lesion complexity, access to coronary physiology and imaging devices, as well as patient management. Thus, there is a need to construct a consensus document on recommendations for use of physiology-guided percutaneous coronary intervention (PCI) in APAC populations. This document serves as an overview of recommendations describing the best practices for APAC populations to achieve more consistent and optimal clinical outcomes. Methods and results: A comprehensive multiple-choice questionnaire was provided to 20 interven- tional cardiologists from 10 countries in the APAC region. Clinical evidence, tips and techniques, and clinical situations for the use of physiology-guided PCI in APAC were reviewed and used to propose key recommendations. There are suggestions to continue to develop evidence for lesion and patient types that will benefit from physiology, develop directions for future research in health economics and local data, develop appropriate use criteria in different countries, and emphasize the importance of education of all stakeholders. A consensus recommendation to enhance the penetration of invasive physiology-based therapy was to adopt the 5E approach: Evidence, Education, Expand hardware, Economics and Expert consensus. Conclusions: This consensus document and recommendations support interventional fellows and cardiologists, hospital administrators, patients, and medical device companies to build confidence and encourage wider implementation of invasive coronary physiology-guided therapy in the APAC region.

Original languageEnglish
Pages (from-to)215-225
Number of pages11
JournalCardiology Journal
Issue number3
Publication statusPublished - May 2019
Externally publishedYes

Bibliographical note

Copyright the Publisher 2019. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.


  • coronary physiology
  • invasive physiologic assessment
  • quality improvement


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