Continuous microfluidic immunomagnetic cell separation

David W. Inglis*, R. Riehn, R. H. Austin, J. C. Sturm

*Corresponding author for this work

Research output: Contribution to journalArticle

294 Citations (Scopus)
22 Downloads (Pure)

Abstract

We present a continuous-flow microfluidic device that enables cell by cell separation of cells selectively tagged with magnetic nanoparticles. The cells flow over an array of microfabricated magnetic stripes, which create a series of high magnetic field gradients that trap the magnetically labeled cells and alter their flow direction. The process was observed in real time using a low power microscope. The device has been demonstrated by the separation of leukocytes from whole human blood.

Original languageEnglish
Pages (from-to)5093-5095
Number of pages3
JournalApplied Physics Letters
Volume85
Issue number21
DOIs
Publication statusPublished - Nov 2004
Externally publishedYes

Bibliographical note

Copyright (2004) American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Applied Physics Letters, 85:21, 5093-5095 and may be found at http://dx.doi.org/10.1063/1.1823015.

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