Abstract
We present a continuous-flow microfluidic device that enables cell by cell separation of cells selectively tagged with magnetic nanoparticles. The cells flow over an array of microfabricated magnetic stripes, which create a series of high magnetic field gradients that trap the magnetically labeled cells and alter their flow direction. The process was observed in real time using a low power microscope. The device has been demonstrated by the separation of leukocytes from whole human blood.
Original language | English |
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Pages (from-to) | 5093-5095 |
Number of pages | 3 |
Journal | Applied Physics Letters |
Volume | 85 |
Issue number | 21 |
DOIs | |
Publication status | Published - Nov 2004 |
Externally published | Yes |