Projects per year
Abstract
Upconversion nanoparticles (UCNPs) exhibit unique optical properties such as photo-emission stability, large anti-Stokes shift, and long excited-state lifetimes, allowing significant advances in a broad range of applications from biomedical sensing to super-resolution microscopy. In recent years, progress on nanoparticle synthesis led to the development of many strategies for enhancing their upconversion luminescence, focused in particular on heavy doping of lanthanide ions and core–shell structures. In this article, we investigate the non-linear emission properties of fully Yb-based core–shell UCNPs and their impact on the super-resolution performance of stimulated excitation-depletion (STED) microscopy and super-linear excitation-emission (uSEE) microscopy. Controlling the power-dependent emission curve enables us to relax constraints on the doping concentrations and to reduce the excitation power required for accessing sub-diffraction regimes. We take advantage of this feature to implement multiplexed super-resolution imaging of a two-sample mixture.
Original language | English |
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Pages (from-to) | 20347-20355 |
Number of pages | 9 |
Journal | Nanoscale |
Volume | 12 |
Issue number | 39 |
Early online date | 28 Sept 2020 |
DOIs | |
Publication status | Published - 21 Oct 2020 |
Bibliographical note
Copyright © The Royal Society of Chemistry 2020. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.Fingerprint
Dive into the research topics of 'Controlling the non-linear emission of upconversion nanoparticles to enhance super-resolution imaging performance'. Together they form a unique fingerprint.Projects
- 3 Active
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Seeing deeply inside the body with the world's smallest microscope
Ploschner, M.
1/03/17 → …
Project: Research
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Hyper-domain luminescence lifetime imaging for mapping molecular dynamics
1/02/17 → …
Project: Research
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ARC CoE Nanoscale BioPhotonics (CNBP) (RAAP)
Piper, J., Goldys, E., Packer, N. & Jin, D.
20/06/14 → …
Project: Research