Coronary artery bypass grafting with and without manipulation of the ascending aorta - A meta-analysis

J. James Edelman; Tristan D. Yan; Paul G. Bannon; Michael K. Wilson; Michael P. Vallely

doi:10.1016/j.hlc.2011.02.003

Coronary artery bypass grafting with and without manipulation of the ascending aorta - A meta-analysis

J. James Edelman^*, Tristan D. Yan, Paul G. Bannon, Michael K. Wilson, Michael P. Vallely

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

58 Citations (Scopus)

Abstract

Background: The main criticism of surgery in the SYNTAX trial was increased rate of stroke when compared to percutaneous coronary intervention. We aimed to determine whether avoiding aortic manipulation would decrease the rate of stroke. Method: We performed a meta-analysis of seven studies comparing coronary artery bypass grafting (CABG) with and without manipulation of the ascending aorta. Results: When anaortic off-pump coronary artery bypass grafting (OPCAB) was compared with conventional CABG, the rate of stroke was 0.38% vs. 1.87% (p< 0.0001). When anaortic OPCAB was compared with OPCAB using a side-clamp or proximal graft anastomosis device the rate of stroke was 0.31% vs. 1.35% (p= 0.003). Conclusion: Avoiding aortic manipulation during CABG may decrease the rate of peri-operative stroke.

Original language	English
Pages (from-to)	318-324
Number of pages	7
Journal	Heart, Lung and Circulation
Volume	20
Issue number	5
DOIs	https://doi.org/10.1016/j.hlc.2011.02.003
Publication status	Published - May 2011
Externally published	Yes

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10.1016/j.hlc.2011.02.003

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title = "Coronary artery bypass grafting with and without manipulation of the ascending aorta - A meta-analysis",

abstract = "Background: The main criticism of surgery in the SYNTAX trial was increased rate of stroke when compared to percutaneous coronary intervention. We aimed to determine whether avoiding aortic manipulation would decrease the rate of stroke. Method: We performed a meta-analysis of seven studies comparing coronary artery bypass grafting (CABG) with and without manipulation of the ascending aorta. Results: When anaortic off-pump coronary artery bypass grafting (OPCAB) was compared with conventional CABG, the rate of stroke was 0.38% vs. 1.87% (p< 0.0001). When anaortic OPCAB was compared with OPCAB using a side-clamp or proximal graft anastomosis device the rate of stroke was 0.31% vs. 1.35% (p= 0.003). Conclusion: Avoiding aortic manipulation during CABG may decrease the rate of peri-operative stroke.",

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T1 - Coronary artery bypass grafting with and without manipulation of the ascending aorta - A meta-analysis

AU - Edelman, J. James

AU - Yan, Tristan D.

AU - Bannon, Paul G.

AU - Wilson, Michael K.

AU - Vallely, Michael P.

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AB - Background: The main criticism of surgery in the SYNTAX trial was increased rate of stroke when compared to percutaneous coronary intervention. We aimed to determine whether avoiding aortic manipulation would decrease the rate of stroke. Method: We performed a meta-analysis of seven studies comparing coronary artery bypass grafting (CABG) with and without manipulation of the ascending aorta. Results: When anaortic off-pump coronary artery bypass grafting (OPCAB) was compared with conventional CABG, the rate of stroke was 0.38% vs. 1.87% (p< 0.0001). When anaortic OPCAB was compared with OPCAB using a side-clamp or proximal graft anastomosis device the rate of stroke was 0.31% vs. 1.35% (p= 0.003). Conclusion: Avoiding aortic manipulation during CABG may decrease the rate of peri-operative stroke.

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Coronary artery bypass grafting with and without manipulation of the ascending aorta - A meta-analysis

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