Coronary artery bypass grafting with and without manipulation of the ascending aorta - A meta-analysis

J. James Edelman*, Tristan D. Yan, Paul G. Bannon, Michael K. Wilson, Michael P. Vallely

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

52 Citations (Scopus)

Abstract

Background: The main criticism of surgery in the SYNTAX trial was increased rate of stroke when compared to percutaneous coronary intervention. We aimed to determine whether avoiding aortic manipulation would decrease the rate of stroke. Method: We performed a meta-analysis of seven studies comparing coronary artery bypass grafting (CABG) with and without manipulation of the ascending aorta. Results: When anaortic off-pump coronary artery bypass grafting (OPCAB) was compared with conventional CABG, the rate of stroke was 0.38% vs. 1.87% (p< 0.0001). When anaortic OPCAB was compared with OPCAB using a side-clamp or proximal graft anastomosis device the rate of stroke was 0.31% vs. 1.35% (p= 0.003). Conclusion: Avoiding aortic manipulation during CABG may decrease the rate of peri-operative stroke.

Original languageEnglish
Pages (from-to)318-324
Number of pages7
JournalHeart, Lung and Circulation
Volume20
Issue number5
DOIs
Publication statusPublished - May 2011
Externally publishedYes

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