Cross-sectional associations between inflammation, sickness behaviour, health anxiety and self-rated health in a Swedish primary care population

Karin Lodin; Mats Lekander; Predrag Petrovic; Gustav Nilsonne; Erik Hedman-Lagerlöf; Anna Andreasson

doi:10.1177/2058739219844357

Cross-sectional associations between inflammation, sickness behaviour, health anxiety and self-rated health in a Swedish primary care population

Karin Lodin, Mats Lekander, Predrag Petrovic, Gustav Nilsonne, Erik Hedman-Lagerlöf, Anna Andreasson^*

^*Corresponding author for this work

Research output: Contribution to journal › Letter › peer-review

6 Citations (Scopus)

29 Downloads (Pure)

Abstract

This study investigated associations between inflammatory markers, sickness behaviour, health anxiety and self-rated health in 311 consecutive primary care patients. Poor self-rated health was associated with high sickness behaviour (ρ = 0.28, P < 0.001; ρ = 0.42, P = 0.003) and high health anxiety (ρ = 0.31, P < 0.001; ρ = –0.32, P = 0.003). High levels of interleukin 6 were associated with poor self-rated health in men (ρ = 0.26, P = 0.009). Low levels of interleukin-6 were associated with poor self-rated health in women (ρ = –0.15, P = 0.04), but this association was non-significant when adjusted for health anxiety (ρ = –0.08, P = 0.31). These results are consistent with the theory that interoceptive processes draw on both inflammatory mediators and the state of sickness behaviour in inferring health state.

Original language	English
Pages (from-to)	1-6
Number of pages	6
Journal	European Journal of Inflammation
Volume	17
DOIs	https://doi.org/10.1177/2058739219844357
Publication status	Published - 1 Jan 2019

Bibliographical note

Copyright the Author(s) 2019. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

cytokine
health anxiety
inflammation
self-rated health
sickness behaviour

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10.1177/2058739219844357Licence: CC BY-NC

Publisher version (open access)Final published version, 499 KBLicence: CC BY-NC

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title = "Cross-sectional associations between inflammation, sickness behaviour, health anxiety and self-rated health in a Swedish primary care population",

abstract = "This study investigated associations between inflammatory markers, sickness behaviour, health anxiety and self-rated health in 311 consecutive primary care patients. Poor self-rated health was associated with high sickness behaviour (ρ = 0.28, P < 0.001; ρ = 0.42, P = 0.003) and high health anxiety (ρ = 0.31, P < 0.001; ρ = –0.32, P = 0.003). High levels of interleukin 6 were associated with poor self-rated health in men (ρ = 0.26, P = 0.009). Low levels of interleukin-6 were associated with poor self-rated health in women (ρ = –0.15, P = 0.04), but this association was non-significant when adjusted for health anxiety (ρ = –0.08, P = 0.31). These results are consistent with the theory that interoceptive processes draw on both inflammatory mediators and the state of sickness behaviour in inferring health state.",

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AU - Lodin, Karin

AU - Lekander, Mats

AU - Petrovic, Predrag

AU - Nilsonne, Gustav

AU - Hedman-Lagerlöf, Erik

AU - Andreasson, Anna

N1 - Copyright the Author(s) 2019. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - This study investigated associations between inflammatory markers, sickness behaviour, health anxiety and self-rated health in 311 consecutive primary care patients. Poor self-rated health was associated with high sickness behaviour (ρ = 0.28, P < 0.001; ρ = 0.42, P = 0.003) and high health anxiety (ρ = 0.31, P < 0.001; ρ = –0.32, P = 0.003). High levels of interleukin 6 were associated with poor self-rated health in men (ρ = 0.26, P = 0.009). Low levels of interleukin-6 were associated with poor self-rated health in women (ρ = –0.15, P = 0.04), but this association was non-significant when adjusted for health anxiety (ρ = –0.08, P = 0.31). These results are consistent with the theory that interoceptive processes draw on both inflammatory mediators and the state of sickness behaviour in inferring health state.

AB - This study investigated associations between inflammatory markers, sickness behaviour, health anxiety and self-rated health in 311 consecutive primary care patients. Poor self-rated health was associated with high sickness behaviour (ρ = 0.28, P < 0.001; ρ = 0.42, P = 0.003) and high health anxiety (ρ = 0.31, P < 0.001; ρ = –0.32, P = 0.003). High levels of interleukin 6 were associated with poor self-rated health in men (ρ = 0.26, P = 0.009). Low levels of interleukin-6 were associated with poor self-rated health in women (ρ = –0.15, P = 0.04), but this association was non-significant when adjusted for health anxiety (ρ = –0.08, P = 0.31). These results are consistent with the theory that interoceptive processes draw on both inflammatory mediators and the state of sickness behaviour in inferring health state.

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JO - European Journal of Inflammation

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ER -

Cross-sectional associations between inflammation, sickness behaviour, health anxiety and self-rated health in a Swedish primary care population

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Keywords

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