Cupula-inspired hyaluronic acid-based hydrogel encapsulation to form biomimetic MEMS flow sensors

Ajay Giri Prakash Kottapalli*, Meghali Bora, Elgar Kanhere, Mohsen Asadnia, Jianmin Miao, Michael S. Triantafyllou

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    10 Citations (Scopus)
    33 Downloads (Pure)

    Abstract

    Blind cavefishes are known to detect objects through hydrodynamic vision enabled by arrays of biological flow sensors called neuromasts. This work demonstrates the development of a MEMS artificial neuromast sensor that features a 3D polymer hair cell that extends into the ambient flow. The hair cell is monolithically fabricated at the center of a 2 µm thick silicon membrane that is photo-patterned with a full-bridge bias circuit. Ambient flow variations exert a drag force on the hair cell, which causes a displacement of the sensing membrane. This in turn leads to the resistance imbalance in the bridge circuit generating a voltage output. Inspired by the biological neuromast, a biomimetic synthetic hydrogel cupula is incorporated on the hair cell. The morphology, swelling behavior, porosity and mechanical properties of the hyaluronic acid hydrogel are characterized through rheology and nanoindentation techniques. The sensitivity enhancement in the sensor output due to the material and mechanical contributions of the micro-porous hydrogel cupula is investigated through experiments.

    Original languageEnglish
    Article number1728
    Pages (from-to)1-14
    Number of pages14
    JournalSensors
    Volume17
    Issue number8
    DOIs
    Publication statusPublished - 1 Aug 2017

    Bibliographical note

    Copyright 2017 by the authors. Licensee MDPI, Basel, Switzerland. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

    Keywords

    • Biomimetic sensors
    • Flow sensing
    • Hydrogels
    • Microelectromechanical systems

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