Current and developing methods for diagnosing Alzheimer’s disease

Stephanie J. Fuller, Nicholas Carrigan, Hamid R. Sohrabi, Ralph N. Martins

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    2 Citations (Scopus)

    Abstract

    Although Alzheimer’s disease (AD) is the most common cause of dementia in the elderly, a definite diagnosis of AD normally requires post-mortem examination. Without specialised brain scans and other tests that are currently only used for clinical research purposes, the many diagnostic tests that are presently available only result in a diagnosis of ‘probable’ AD. These diagnostic tests are also very time-consuming. This chapter briefly describes the classical post-mortem findings in an AD brain, then discusses the wide variety of current neuropsychological tests, followed by current and developing imaging and biomarker-based clinical diagnostic methods.

    Original languageEnglish
    Title of host publicationNeurodegeneration and Alzheimer’s disease
    Subtitle of host publicationthe role of diabetes, genetics, hormones, and lifestyle
    EditorsRalph N. Martins, Charles S. Brennan, W. M. A. D. Binosha Fernando, Margaret A. Brennan, Stephanie J. Fuller
    Place of PublicationUSA
    PublisherWiley
    Chapter3
    Pages43-87
    Number of pages45
    ISBN (Electronic)9781119356752
    ISBN (Print)9781119356783
    DOIs
    Publication statusPublished - 11 May 2019

    Keywords

    • Alzheimer’s disease diagnosis
    • Cognitive tests
    • Dementia
    • Magnetic resonance imaging
    • Neuroimaging
    • Post-mortem examination

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