Current approaches to quantifying tonic and reflex autonomic outflows controlling cardiovascular function in humans and experimental animals

Ibrahim M. Salman

    Research output: Contribution to journalArticlepeer-review

    9 Citations (Scopus)

    Abstract

    The role of the autonomic nervous system in the pathophysiology of human and experimental models of cardiovascular disease is well established. In the recent years, there have been some rapid developments in the diagnostic approaches used to assess and monitor autonomic functions. Although most of these methods are devoted for research purposes in laboratory animals, many have still found their way to routine clinical practice. To name a few, direct long-term telemetry recording of sympathetic nerve activity (SNA) in rodents, single-unit SNA recording using microneurography in human subjects and spectral analysis of blood pressure and heart rate in both humans and animals have recently received an overwhelming attention. In this article, we therefore provide an overview of the methods and techniques used to assess tonic and reflex autonomic functions in humans and experimental animals, highlighting current advances available and procedure description, limitations and usefulness for diagnostic purposes.
    Original languageEnglish
    Article number84
    Pages (from-to)84-1-84-18
    Number of pages18
    JournalCurrent Hypertension Reports
    Volume17
    Issue number11
    DOIs
    Publication statusPublished - 2015

    Keywords

    • autonomic reflexes
    • sympathetic nerve activity
    • parasympathetic nerve activity
    • blood pressure
    • heart rate
    • cardiovascular function

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