Cytomegalovirus retinitis following dexamethasone intravitreal implant

Sarah G. Chaudhry; Adrian T. Fung

doi:10.1016/j.ajoc.2021.101055

Cytomegalovirus retinitis following dexamethasone intravitreal implant

Sarah G. Chaudhry, Adrian T. Fung^*

^*Corresponding author for this work

Faculty of Medicine, Health and Human Sciences

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

68 Downloads (Pure)

Abstract

Purpose: To describe a case of Cytomegalovirus (CMV) Retinitis in an immunocompetent patient following Dexamethasone Intravitreal Implant (DII). Observations: Retrospective chart review of a single patient. An 80-year-old immunocompetent male presented with floaters in his left eye 10 weeks after his DII. He was noted to have a visual acuity of 20/1200 in his left eye and a panuveitis with CMV retinitis. The patient underwent a vitreous biopsy and given immediate intravitreal foscarnet and an ongoing management regimen of oral valganciclovir for two months. His vision improved to 20/200 and his CMV retinitis resolved. Conclusion and Importance: DII can trigger CMV retinitis in immunocompetent patients.

Original language	English
Article number	101055
Pages (from-to)	1-3
Number of pages	3
Journal	American Journal of Ophthalmology Case Reports
Volume	22
DOIs	https://doi.org/10.1016/j.ajoc.2021.101055
Publication status	Published - Jun 2021

Bibliographical note

Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

Cytomegalovirus (CMV)
Dexamethasone intravitreal implant (DII)
Immunocompetent
Retinitis

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Publisher version (open access)Final published version, 775 KBLicence: CC BY-NC-ND

Cite this

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title = "Cytomegalovirus retinitis following dexamethasone intravitreal implant",

abstract = "Purpose: To describe a case of Cytomegalovirus (CMV) Retinitis in an immunocompetent patient following Dexamethasone Intravitreal Implant (DII). Observations: Retrospective chart review of a single patient. An 80-year-old immunocompetent male presented with floaters in his left eye 10 weeks after his DII. He was noted to have a visual acuity of 20/1200 in his left eye and a panuveitis with CMV retinitis. The patient underwent a vitreous biopsy and given immediate intravitreal foscarnet and an ongoing management regimen of oral valganciclovir for two months. His vision improved to 20/200 and his CMV retinitis resolved. Conclusion and Importance: DII can trigger CMV retinitis in immunocompetent patients.",

keywords = "Cytomegalovirus (CMV), Dexamethasone intravitreal implant (DII), Immunocompetent, Retinitis",

author = "Chaudhry, {Sarah G.} and Fung, {Adrian T.}",

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AU - Fung, Adrian T.

N1 - Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

PY - 2021/6

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N2 - Purpose: To describe a case of Cytomegalovirus (CMV) Retinitis in an immunocompetent patient following Dexamethasone Intravitreal Implant (DII). Observations: Retrospective chart review of a single patient. An 80-year-old immunocompetent male presented with floaters in his left eye 10 weeks after his DII. He was noted to have a visual acuity of 20/1200 in his left eye and a panuveitis with CMV retinitis. The patient underwent a vitreous biopsy and given immediate intravitreal foscarnet and an ongoing management regimen of oral valganciclovir for two months. His vision improved to 20/200 and his CMV retinitis resolved. Conclusion and Importance: DII can trigger CMV retinitis in immunocompetent patients.

AB - Purpose: To describe a case of Cytomegalovirus (CMV) Retinitis in an immunocompetent patient following Dexamethasone Intravitreal Implant (DII). Observations: Retrospective chart review of a single patient. An 80-year-old immunocompetent male presented with floaters in his left eye 10 weeks after his DII. He was noted to have a visual acuity of 20/1200 in his left eye and a panuveitis with CMV retinitis. The patient underwent a vitreous biopsy and given immediate intravitreal foscarnet and an ongoing management regimen of oral valganciclovir for two months. His vision improved to 20/200 and his CMV retinitis resolved. Conclusion and Importance: DII can trigger CMV retinitis in immunocompetent patients.

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KW - Immunocompetent

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Cytomegalovirus retinitis following dexamethasone intravitreal implant

Abstract

Bibliographical note

Keywords

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