Cytomegalovirus retinitis following dexamethasone intravitreal implant

Sarah G. Chaudhry; Adrian T. Fung

doi:10.1016/j.ajoc.2021.101055

Cytomegalovirus retinitis following dexamethasone intravitreal implant

Sarah G. Chaudhry, Adrian T. Fung^*

^*Corresponding author for this work

Faculty of Medicine, Health and Human Sciences

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

48 Downloads (Pure)

Abstract

Purpose: To describe a case of Cytomegalovirus (CMV) Retinitis in an immunocompetent patient following Dexamethasone Intravitreal Implant (DII). Observations: Retrospective chart review of a single patient. An 80-year-old immunocompetent male presented with floaters in his left eye 10 weeks after his DII. He was noted to have a visual acuity of 20/1200 in his left eye and a panuveitis with CMV retinitis. The patient underwent a vitreous biopsy and given immediate intravitreal foscarnet and an ongoing management regimen of oral valganciclovir for two months. His vision improved to 20/200 and his CMV retinitis resolved. Conclusion and Importance: DII can trigger CMV retinitis in immunocompetent patients.

Original language	English
Article number	101055
Pages (from-to)	1-3
Number of pages	3
Journal	American Journal of Ophthalmology Case Reports
Volume	22
DOIs	https://doi.org/10.1016/j.ajoc.2021.101055
Publication status	Published - Jun 2021

Bibliographical note

Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

Cytomegalovirus (CMV)
Dexamethasone intravitreal implant (DII)
Immunocompetent
Retinitis

Access to Document

10.1016/j.ajoc.2021.101055Licence: CC BY-NC-ND

Publisher version (open access)Final published version, 775 KBLicence: CC BY-NC-ND

Cite this

@article{71eb287fab744bfc9a9d08c8eab41f7f,

title = "Cytomegalovirus retinitis following dexamethasone intravitreal implant",

abstract = "Purpose: To describe a case of Cytomegalovirus (CMV) Retinitis in an immunocompetent patient following Dexamethasone Intravitreal Implant (DII). Observations: Retrospective chart review of a single patient. An 80-year-old immunocompetent male presented with floaters in his left eye 10 weeks after his DII. He was noted to have a visual acuity of 20/1200 in his left eye and a panuveitis with CMV retinitis. The patient underwent a vitreous biopsy and given immediate intravitreal foscarnet and an ongoing management regimen of oral valganciclovir for two months. His vision improved to 20/200 and his CMV retinitis resolved. Conclusion and Importance: DII can trigger CMV retinitis in immunocompetent patients.",

keywords = "Cytomegalovirus (CMV), Dexamethasone intravitreal implant (DII), Immunocompetent, Retinitis",

author = "Chaudhry, \{Sarah G.\} and Fung, \{Adrian T.\}",

note = "Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.",

year = "2021",

month = jun,

doi = "10.1016/j.ajoc.2021.101055",

language = "English",

volume = "22",

pages = "1--3",

journal = "American Journal of Ophthalmology Case Reports",

issn = "2451-9936",

publisher = "Elsevier",

}

TY - JOUR

T1 - Cytomegalovirus retinitis following dexamethasone intravitreal implant

AU - Chaudhry, Sarah G.

AU - Fung, Adrian T.

N1 - Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

PY - 2021/6

Y1 - 2021/6

N2 - Purpose: To describe a case of Cytomegalovirus (CMV) Retinitis in an immunocompetent patient following Dexamethasone Intravitreal Implant (DII). Observations: Retrospective chart review of a single patient. An 80-year-old immunocompetent male presented with floaters in his left eye 10 weeks after his DII. He was noted to have a visual acuity of 20/1200 in his left eye and a panuveitis with CMV retinitis. The patient underwent a vitreous biopsy and given immediate intravitreal foscarnet and an ongoing management regimen of oral valganciclovir for two months. His vision improved to 20/200 and his CMV retinitis resolved. Conclusion and Importance: DII can trigger CMV retinitis in immunocompetent patients.

AB - Purpose: To describe a case of Cytomegalovirus (CMV) Retinitis in an immunocompetent patient following Dexamethasone Intravitreal Implant (DII). Observations: Retrospective chart review of a single patient. An 80-year-old immunocompetent male presented with floaters in his left eye 10 weeks after his DII. He was noted to have a visual acuity of 20/1200 in his left eye and a panuveitis with CMV retinitis. The patient underwent a vitreous biopsy and given immediate intravitreal foscarnet and an ongoing management regimen of oral valganciclovir for two months. His vision improved to 20/200 and his CMV retinitis resolved. Conclusion and Importance: DII can trigger CMV retinitis in immunocompetent patients.

KW - Cytomegalovirus (CMV)

KW - Dexamethasone intravitreal implant (DII)

KW - Immunocompetent

KW - Retinitis

UR - https://www.scopus.com/pages/publications/85102030232

U2 - 10.1016/j.ajoc.2021.101055

DO - 10.1016/j.ajoc.2021.101055

M3 - Article

C2 - 33732951

AN - SCOPUS:85102030232

SN - 2451-9936

VL - 22

SP - 1

EP - 3

JO - American Journal of Ophthalmology Case Reports

JF - American Journal of Ophthalmology Case Reports

M1 - 101055

ER -

Cytomegalovirus retinitis following dexamethasone intravitreal implant

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this