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Definitions and validation criteria for biomarkers and surrogate endpoints: development and testing of a quantitative hierarchical levels of evidence schema

Marissa N. Lassere*, Kent R. Johnson, Maarten Boers, Peter Tugwell, Peter Brooks, Lee Simon, Vibeke Strand, Philip G. Conaghan, Mikkel Østergaard, Walter P. Maksymowych, Robert Landewé, Barry Bresnihan, Paul-Peter Tak, Richard Wakefield, Philip Mease, Clifton O. Bingham III, Michael Hughes, Doug Altman, Marc Buyse, Sally GalbraithGeorge Wells

*Corresponding author for this work

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